Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23037 | 0.82 | CRHR1 (0.38) | CRHR1 | |
| SCHEMBL9193841 | 0.73 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL8025137 | 0.71 | EGFR (0.37) | CRHR1 | |
| SCHEMBL9728674 | 0.71 | EGFR (0.39) | CRHR1 | |
| SCHEMBL9837138 | 0.70 | EGFR (0.47) | — | |
| SCHEMBL9728970 | 0.69 | EGFR (0.40) | — | |
| SCHEMBL11289908 | 0.68 | LMNA (0.41) | CRHR1 | |
| SCHEMBL11282132 | 0.68 | AKT1 (0.44) | — | |
| SCHEMBL9729031 | 0.68 | EGFR (0.36) | CRHR1 | |
| Dimethirimol SCHEMBL54527 | 0.67 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730115-B1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | MERIAL LTD (US) | 2010-06-09 | — | — | EP | disclosed |
| US-7659288-B2 | 5-[N-Methyl-N-(phthalimidomethyl)amino]-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinylpyrazole; used in oral form so as to prevent the possible contamination of humans or the surrounding environment; used in lower dose | MERIAL LIMITED (US) | 2010-02-09 | — | — | US | disclosed |
| US-20070149575-A1 | 5-Aminoalkylpyrazole derivatives as pesticidal agents | MERIAL, INC. | 2007-06-28 | — | — | US | disclosed |
| EP-1730115-A1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | Merial Ltd. (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005090312-A1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | MERIAL LTD. (US) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149575-A1 | 5-Aminoalkylpyrazole derivatives as pesticidal agents | DDT, AASDHPPT, ACHE | FAAH 712/4885CRHR1 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.