Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107634 | 0.85 | — | — | |
| SCHEMBL29613654 | 0.85 | NPC1 (0.35) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL373843 | 0.85 | NPC1 (0.35) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL8397404 | 0.84 | TDP1 (0.37) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL11668078 | 0.80 | CA2 (0.41) | ALDH1A1MAPTTDP1SMN1; SMN2NPSR1 | |
| SCHEMBL9467298 | 0.78 | CYP1A2 (0.34) | MAPTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL345853 | 0.78 | MAPT (0.35) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL8400550 | 0.77 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL23638712 | 0.76 | NPC1 (0.37) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL2238210 | 0.76 | POLB (0.33) | TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750157-B1 | CONTACT LENS | MENICON CO LTD (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-7588334-B2 | Contact lens | MENICON CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| US-20070232755-A1 | Contact Lens | MENICON CO., LTD. (JP) | 2007-10-04 | — | — | US | disclosed |
| EP-1750157-A1 | CONTACT LENS | MENICON CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |