SCHEMBL3371360

SCHEMBL3371360

Cc1ncc(COP(=O)(O)O)c(N)n1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
TDP1 Q9NUW8 2/20 0.54
ESR1 P03372 1/20 0.49
PTGS1 P23219 1/20 0.49
ACP1 P24666 1/20 0.49
PDE4A P27815 1/20 0.49
P2RX1 P51575 1/20 0.49
P2RX2 Q9UBL9 1/20 0.49
PNPO Q9NVS9 1/20 0.48
TKT P29401 5/20 0.47
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
PDE4D Q08499 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL851328 0.88 LMNA (0.57) LMNATDP1ESR1PTGS1ACP1
Pyrophosphoric Acid SCHEMBL851327 0.80 LMNA (0.51) LMNATDP1TKT
SCHEMBL5916304 0.79 LMNA (0.50) LMNATDP1TKTCYP3A4CYP2C19
Phosphoric Acid SCHEMBL1533803 0.79 LMNA (0.53) LMNATDP1TKT
Phosphoric Acid SCHEMBL851329 0.79 LMNA (0.53) LMNATDP1TKT
SCHEMBL849877 0.79 LMNA (0.53) LMNATDP1TKT
SCHEMBL7607052 0.76 LMNA (1.00) LMNATKT
SCHEMBL18987265 0.74 LMNA (0.65) LMNATKT
SCHEMBL20323319 0.74 ESR1 (0.66) LMNATDP1ESR1PTGS1ACP1
SCHEMBL12346332 0.74 LMNA (0.63) LMNATKT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022411-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE BIOSYNTIA APS (DK) 2026-01-22 US claimed
EP-4555076-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE Biosyntia ApS (DK) 2025-05-21 EP claimed
CN-119731312-A Microbial cell factory for producing thiamine 拜奥信尼亚私营有限责任公司 2025-03-28 CN claimed
US-20240368659-A1 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2024-11-07 US claimed
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 EP claimed
WO-2024013212-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE BIOSYNTIA APS (DK) 2024-01-18 WO claimed
WO-2023285585-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2023-01-19 WO claimed
US-10696992-B2 Genetically modified bacterial cell factory for thiamine production BIOSYNTHIA APS (DK) 2020-06-30 US claimed
EP-3390618-B1 A GENETICALLY MODIFIED BACTERIAL CELL FACTORY FOR THIAMINE PRODUCTION BIOSYNTIA APS (DK) 2020-04-22 EP claimed
EP-3390618-A1 A GENETICALLY MODIFIED BACTERIAL CELL FACTORY FOR THIAMINE PRODUCTION Biosyntia ApS (DK) 2018-10-24 EP claimed
WO-2017103221-A1 A GENETICALLY MODIFIED BACTERIAL CELL FACTORY FOR THIAMINE PRODUCTION BIOSYNTIA APS (DK) 2017-06-22 WO claimed
EP-1093520-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING Syngenta Participations AG (CH) 2001-04-25 EP claimed
WO-2000000623-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING SYNGENTA PARTICIPATIONS AG (CH) 2000-01-06 WO claimed
WO-2026099311-A2 MICROBIAL CELL FACTORIES PRODUCING PROSTAGLANDINS RIVER STONE BIOTECH APS (DK) 2026-05-15 WO disclosed
US-20260022411-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE BIOSYNTIA APS (DK) 2026-01-22 US disclosed
EP-4555076-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE Biosyntia ApS (DK) 2025-05-21 EP disclosed
US-20060127993-A1 Thiamin production by fermentation DSM IP ASSETS B.V. (NL) 2006-06-15 US disclosed
US-20050287169-A1 Methods of use of genes of pyridoxal 5'-phosphate biosynthesis in Bacillus subtilis: avirulent strains for vaccines, and methods for identification of antibacterial agents NATIONAL SCIENCE FOUNDATION 2005-12-29 US disclosed
EP-1093520-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING Syngenta Participations AG (CH) 2001-04-25 EP disclosed
WO-2000000623-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING SYNGENTA PARTICIPATIONS AG (CH) 2000-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022411-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE AHCY, SHMT1, MTHFD1 LMNA 4260/4885TDP1 1224/4885ESR1 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.