Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 8/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 7/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292473 | 0.71 | OR51E2 (0.53) | FEN1ERCC5HAO1OR51E2PTPN1 | |
| SCHEMBL7698150 | 0.70 | KMT2A (0.31) | — | |
| SCHEMBL19423 | 0.67 | — | — | |
| Oxaloacetate SCHEMBL812075 | 0.67 | LDHA (0.50) | FEN1ERCC5HAO1OR51E2PTPN1 | |
| SCHEMBL16627942 | 0.67 | — | — | |
| Oxaloacetate SCHEMBL898612 | 0.65 | LDHA (0.57) | FEN1ERCC5HAO1OR51E2PTPN1 | |
| Oxaloacetate SCHEMBL8464 | 0.65 | — | — | |
| Oxaloacetate SCHEMBL4298763 | 0.65 | LDHA (0.57) | FEN1ERCC5HAO1OR51E2PTPN1 | |
| Oxaloacetate SCHEMBL27856690 | 0.65 | TP53 (0.42) | FEN1ERCC5HAO1OR51E2PTPN1 | |
| SCHEMBL596299 | 0.65 | EGLN1 (0.42) | FEN1ERCC5HAO1OR51E2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100159540-A1 | SYNTHESIS OF RESOLVINS AND INTERMEDIATES, COMPOUNDS PREPARED THEREBY, AND USES THEREOF | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100159540-A1 | SYNTHESIS OF RESOLVINS AND INTERMEDIATES, COMPOUNDS PREPARED THEREBY, AND USES THEREOF | ALOX5, ALOX15, ALOX15B | FEN1 3319/4885ERCC5 2071/4885HAO1 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.