Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12359393 | 0.84 | FKBP1A (1.00) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL8320871 | 0.84 | ALDH1A1 (0.79) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL13640045 | 0.82 | FKBP1A (0.80) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL13534672 | 0.81 | FKBP1A (0.92) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL2712996 | 0.81 | FKBP1A (0.74) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL15919449 | 0.81 | FKBP1A (0.74) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL9041797 | 0.81 | ALDH1A1 (0.74) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL5692472 | 0.79 | ALDH1A1 (1.00) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL2554461 | 0.79 | FKBP1A (0.70) | FKBP1APOLBALDH1A1HPGDUSP2 | |
| SCHEMBL335195 | 0.79 | FKBP1A (0.74) | FKBP1APOLBALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509566-B2 | PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2022-03-09 | — | — | EP | disclosed |
| EP-2346484-B1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2019-11-06 | — | — | EP | disclosed |
| EP-2509566-B1 | PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2018-08-22 | — | — | EP | disclosed |
| EP-2424490-B1 | COMPOSITION FOR PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2017-06-28 | — | — | EP | disclosed |
| EP-2358441-B1 | BLEACHING/HIGHLIGHTING COMPOSITION | KAO GERMANY GMBH (DE) | 2017-06-14 | — | — | EP | disclosed |
| US-9662289-B2 | Process for permanent shaping of human hair | KAO GERMANY GMBH (DE) | 2017-05-30 | — | — | US | disclosed |
| US-20170000700-A1 | BLEACHING/HIGHLIGHTING COMPOSITION | KAO GERMANY GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| EP-2515844-B1 | PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR | KAO GERMANY GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20140246042-A1 | Process for Permanent Shaping of Human Hair | KAO GERMANY GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-8753616-B2 | Process for permanent shaping of human hair | KAO GERMANY GMBH (DE) | 2014-06-17 | — | — | US | disclosed |
| EP-2191863-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| EP-2191867-A1 | Bleaching/Highlighting composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2010046076-A1 | COMPOSITION FOR THE PERMANENT SHAPING OF HUMAN HAIR | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2010-04-29 | — | — | WO | disclosed |
| EP-2177206-A1 | Composition for the permanent shaping of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-04-21 | — | — | EP | disclosed |
| US-7612212-B2 | 2-[(S)-2-((S)-2,5-dioxo-4-phenyl-imidazolidin-1-yl)-4-methyl-pentanoylamino]-thiazole-4-carboxylic acid methyl ester; mitogen activated protein/extracellular signal regulated kinase kinase inhibitor; anticarcinogenic agent, cognition activator, nervous and autoimmune system disorders | HOFFMANN-LA ROCHE INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1989186-A1 | HYDANTOIN BASED KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-12 | — | — | EP | disclosed |
| WO-2008101840-A1 | COMBINATION OF ERLOTINIB AND MEK-INHIBITORS FOR INHIBITING PROLIFERATION OF TUMOR CELLS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-28 | — | — | WO | disclosed |
| US-20080207563-A1 | METHOD FOR INHIBITING PROLIFERATION OF TUMOR CELLS | NIU HUIFENG | 2008-08-28 | — | — | US | disclosed |
| WO-2007096259-A1 | HYDANTOIN BASED KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-30 | — | — | WO | disclosed |
| US-20070197617-A1 | Substituted hydantoins | CHEN SHAOQING | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197617-A1 | Substituted hydantoins | HNMT, HRH3, BRAF | FKBP1A 3588/4885POLB 3679/4885ALDH1A1 963/4885 |
| US-20140246042-A1 | Process for Permanent Shaping of Human Hair | POLR1C, PRKDC, PRKACG | FKBP1A 3686/4885POLB 48/4885ALDH1A1 185/4885 |
| US-20170000700-A1 | BLEACHING/HIGHLIGHTING COMPOSITION | CRYAB, CUTA, CSTB | FKBP1A 1587/4885POLB 315/4885ALDH1A1 1560/4885 |
| US-20080207563-A1 | METHOD FOR INHIBITING PROLIFERATION OF TUMOR CELLS | MKI67, BRAF, MYC | FKBP1A 1815/4885POLB 1241/4885ALDH1A1 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.