Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.64 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.64 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5234462 | 0.88 | SIGMAR1 (0.65) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| SCHEMBL7055109 | 0.86 | CARM1 (0.75) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| SCHEMBL9686059 | 0.86 | SIGMAR1 (0.68) | CARM1PRMT6PRMT8SIGMAR1MAOB | |
| SCHEMBL294657 | 0.82 | ALDH1A1 (0.58) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| SCHEMBL1088446 | 0.82 | SIGMAR1 (0.74) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| Dibemethine SCHEMBL276863 | 0.81 | ALDH1A1 (0.70) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| Dibemethine SCHEMBL10542007 | 0.81 | ALDH1A1 (0.70) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| SCHEMBL6785426 | 0.81 | SIGMAR1 (0.63) | SIGMAR1AOC3 | |
| Hydrochloric Acid SCHEMBL1087168 | 0.80 | SIGMAR1 (0.71) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 | |
| SCHEMBL8221303 | 0.80 | CARM1 (0.67) | CARM1PRMT6PRMT8SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781919-B | As the amido acridine derivatives of the selective depressant of ubiquitin-specific protease 7 | HYBRIGENICS S.A. (FR) | 2016-01-20 | — | — | CN | claimed |
| CN-102781919-A | Amidoacridine derivatives useful as selective inhibitors of ubiquitin specific protease 7 | HYBRIGENICS SA | 2012-11-14 | — | — | CN | claimed |
| WO-2009133180-A1 | NICARDIPINE HYDROCHLORIDE DIHYDRATE AND CHLOROFORMATE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (75%) (ES) | 2009-11-05 | — | — | WO | claimed |
| EP-0328000-B1 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GOEDECKE AG (DE) | 1995-01-18 | — | — | EP | claimed |
| US-5380746-A | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | claimed |
| WO-1993024490-A1 | USE OF INDOLOCARBAZOLS IN AIDS TREATMENT | Gödecke Aktiengesellschaft (DE) | 1993-12-09 | — | — | WO | claimed |
| EP-0370236-B1 | INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-12-27 | — | — | EP | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | claimed |
| US-4958024-A | REACTION OF CARBAMATE SUBSTITUTED ACRYLIC ESTER, VASODILATORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-09-18 | — | — | US | claimed |
| US-4914227-A | FOR VASODILATING AND HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-04-03 | — | — | US | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| CN-1035667-A | Indolocarbazole derivative and preparation method thereof and pharmaceutical composition | GOEDECKE AG (DE) | 1989-09-20 | — | — | CN | claimed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | claimed |
| US-4739106-A | VASODILATION, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0101023-B1 | PROCESS FOR PREPARING 2-CARBAMOYLOXYALKYL-1,4-DIHYDROPYRIDINE DERIVATIVES AND INTERMEDIATES USEFUL FOR THE PROCESS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | claimed |
| CN-109563186-B | Method for producing modified conjugated diene polymer and method for producing polymer composition | 住友化学株式会社 | 2022-04-15 | — | — | CN | disclosed |
| CN-107428665-B | Method for producing (meth) acrylic ester | 东亚合成株式会社 | 2021-10-15 | — | — | CN | disclosed |
| EP-0035711-A2 | 10-Substituted-5-cyanomethylene-dibenzo-(a,d)cycloheptenes, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | disclosed |
| EP-0019172-A1 | 6-Substituted 11-alkylene-morphantridines, process for preparing them and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-11-26 | — | — | EP | disclosed |