SCHEMBL3379303

SCHEMBL3379303

CCc1cccc(CC)c1NS(=O)(=O)C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.49
PTGS2 P35354 3/20 0.49
PTPN11 Q06124 1/20 0.43
CA2 P00918 4/20 0.42
GABRA1 P14867 2/20 0.42
GABRB2 P47870 2/20 0.42
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PTPN1 P18031 1/20 0.41
SCN5A Q14524 3/20 0.38
CACNA1C Q13936 2/20 0.38
CA1 P00915 1/20 0.38
HSD11B1 P28845 1/20 0.38
KCNH2 Q12809 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5570704 0.85 CA2 (0.47) PTGS1PTGS2CA2SMN1; SMN2CA1
SCHEMBL12601600 0.83 GABRA1 (0.43) GABRA1GABRB2SCN5ACACNA1CHSD11B1
SCHEMBL23674206 0.77 TSHR (0.53) PTGS1PTGS2PTPN11CA2MAPK1
SCHEMBL27183002 0.73 GABRA1 (0.40) GABRA1GABRB2SCN5ACACNA1CKCNH2
SCHEMBL23674205 0.73 L3MBTL1 (0.43) PTPN11CA2MAPK1SMN1; SMN2
SCHEMBL19567186 0.73 PTGS1 (0.63) PTGS1PTGS2PTPN11CA2MAPK1
SCHEMBL12650118 0.72 KCNH2 (0.41) GABRA1GABRB2SCN5ACACNA1CKCNH2
SCHEMBL11435396 0.70 TGM2 (0.42) GABRA1GABRB2SCN5ACACNA1CKCNH2
SCHEMBL15779690 0.70 PDK1 (0.49) PTGS1PTGS2PTPN11CA2MAPK1
SCHEMBL17553989 0.69 PSIP1 (0.43) PTGS1GABRA1GABRB2MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1305837-B1 GAS SENSORS CITY TECH (GB) 2010-11-17 EP claimed
CN-110300887-A ULTRATHIN ELECTROCHEMICAL GAS SENSOR 霍尼韦尔国际公司 2019-10-01 CN disclosed
US-20190041351-A1 MEMS ELECTROCHEMICAL GAS SENSOR HONEYWELL INTERNATIONAL INC., A DELAWARE CORPORATION 2019-02-07 US disclosed
EP-3387419-A1 ELECTROCHEMICAL SENSOR AND ELECTRONICS ON A CERAMIC SUBSTRATE Honeywell International Inc. (US) 2018-10-17 EP disclosed
US-20180266984-A1 ELECTROCHEMICAL SENSOR AND ELECTRONICS ON A CERAMIC SUBSTRATE HONEYWELL INTERNATIONAL INC., A DELAWARE CORPORATION 2018-09-20 US disclosed
WO-2017099963-A1 ELECTROCHEMICAL SENSOR AND ELECTRONICS ON A CERAMIC SUBSTRATE HONEYWELL INTERNATIONAL INC. (US) 2017-06-15 WO disclosed
EP-1305837-B1 GAS SENSORS CITY TECH (GB) 2010-11-17 EP disclosed
EP-1305837-B1 GAS SENSORS CITY TECH (GB) 2010-11-17 EP disclosed
US-7279080-B2 Gas sensors CITY TECHNOLOGY LIMITED (GB) 2007-10-09 US disclosed
US-7279080-B2 Gas sensors CITY TECHNOLOGY LIMITED (GB) 2007-10-09 US disclosed
US-20040026246-A1 Gas sensors CITY TECHNOLOGY LIMITED (GB) 2004-02-12 US disclosed
US-20040026246-A1 Gas sensors CITY TECHNOLOGY LIMITED (GB) 2004-02-12 US disclosed
EP-1305837-A1 GAS SENSORS CITY TECHNOLOGY LIMITED (GB) 2003-05-02 EP disclosed
EP-1305837-A1 GAS SENSORS CITY TECHNOLOGY LIMITED (GB) 2003-05-02 EP disclosed
WO-2002011225-A1 GAS SENSORS CITY TECHNOLOGY LIMITED (GB) 2002-02-07 WO disclosed
WO-2002011225-A1 GAS SENSORS CITY TECHNOLOGY LIMITED (GB) 2002-02-07 WO disclosed