Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017733 | 0.79 | GAA (0.44) | ALDH1A1L3MBTL1GAACYP1A2 | |
| SCHEMBL127344 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| Hydrochloric Acid SCHEMBL10901278 | 0.71 | TDP1 (0.50) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL4921797 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL8447828 | 0.69 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL3380450 | 0.69 | ALDH1A1 (0.33) | ALDH1A1CYP3A4MAPK1TSHRALOX15 | |
| SCHEMBL476573 | 0.68 | CA12 (0.60) | ALDH1A1CYP3A4TDP1MAPK1L3MBTL1 | |
| SCHEMBL11218745 | 0.68 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL9559165 | 0.68 | MAPT (0.44) | ALDH1A1CYP3A4TDP1MAPK1TSHR | |
| SCHEMBL7590353 | 0.68 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TDP1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943809-B2 | Solvent resistant thin film composite membrane and its preparation | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-04-17 | — | — | US | claimed |
| US-20170065937-A1 | SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-03-09 | — | — | US | claimed |
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | THE PENN STATE RESEARCH FOUNDATION (PA) | 2024-07-16 | — | — | US | disclosed |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION | 2021-12-02 | — | — | US | disclosed |
| EP-3860743-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | The Penn State Research Foundation (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072594-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2020-04-09 | — | — | WO | disclosed |
| US-9943809-B2 | Solvent resistant thin film composite membrane and its preparation | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-04-17 | — | — | US | disclosed |
| US-20170065937-A1 | SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-03-09 | — | — | US | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |
| US-5693227-A | POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS | IONICS, INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | PORCN, MLEC, FLOT1 | ALDH1A1 4875/4885CYP3A4 3165/4885TDP1 3668/4885 |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | PORCN, MLEC, FLOT1 | ALDH1A1 4875/4885CYP3A4 3165/4885TDP1 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.