Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017733 | 0.72 | GAA (0.44) | ALDH1A1GAASMN1; SMN2CYP1A2HPGD | |
| SCHEMBL556848 | 0.71 | C5AR1 (0.37) | ALDH1A1TSHRHSD17B10GAAKMT2A | |
| SCHEMBL3380443 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TSHRGAAKMT2AALOX15 | |
| SCHEMBL28834703 | 0.69 | C5AR1 (0.36) | ALDH1A1TSHRHSD17B10ALOX15CYP3A4 | |
| SCHEMBL3706530 | 0.68 | GAA (0.41) | ALDH1A1GAAKMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL476574 | 0.67 | MAPT (0.42) | ALDH1A1TSHRHSD17B10GAAKMT2A | |
| SCHEMBL2357793 | 0.67 | ESR1 (0.36) | ALDH1A1TSHRHSD17B10KMT2AALOX15 | |
| SCHEMBL21361177 | 0.65 | TLR8 (0.35) | ALDH1A1TSHRKMT2ACYP3A4CYP1A2 | |
| SCHEMBL3375188 | 0.64 | MAPT (0.39) | ALDH1A1TSHRHSD17B10GAAKMT2A | |
| SCHEMBL11037286 | 0.64 | SLC6A2 (0.54) | ALDH1A1TSHRHSD17B10KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943809-B2 | Solvent resistant thin film composite membrane and its preparation | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-04-17 | — | — | US | claimed |
| US-20170065937-A1 | SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-03-09 | — | — | US | claimed |
| US-5693227-A | POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS | IONICS, INCORPORATED (US) | 1997-12-02 | — | — | US | claimed |
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | THE PENN STATE RESEARCH FOUNDATION (PA) | 2024-07-16 | — | — | US | disclosed |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION | 2021-12-02 | — | — | US | disclosed |
| EP-3860743-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | The Penn State Research Foundation (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2020072594-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | THE PENN STATE RESEARCH FOUNDATION (US) | 2020-04-09 | — | — | WO | disclosed |
| US-9943809-B2 | Solvent resistant thin film composite membrane and its preparation | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-04-17 | — | — | US | disclosed |
| US-20170065937-A1 | SOLVENT RESISTANT THIN FILM COMPOSITE MEMBRANE AND ITS PREPARATION | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2017-03-09 | — | — | US | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |
| US-5693227-A | POLYMERIZATION OF MOLECULES HAVING ELECTROPHILIC AND NUCLEOPHILIC SUBSTITUENTS ON THE SAME OR DIFFERENT MOLECULES; REGENERATION OF AMINOPYRIDINE CATALYSTS | IONICS, INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12036515-B2 | Thin-film composite membrane and methods of making and using the same | PORCN, MLEC, FLOT1 | ALDH1A1 4875/4885TSHR 2910/4885HSD17B10 1228/4885 |
| US-20210370240-A1 | THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME | PORCN, MLEC, FLOT1 | ALDH1A1 4875/4885TSHR 2910/4885HSD17B10 1228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.