Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380406 | 1.00 | KDM4E (0.31) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL3381866 | 0.94 | KDM4E (0.30) | KDM4EMAPT | |
| SCHEMBL22247631 | 0.85 | FTO (0.33) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL14078007 | 0.85 | MEN1 (0.32) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL14078004 | 0.85 | KDM4E (0.31) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL9915064 | 0.85 | FTO (0.43) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL1095520 | 0.85 | FTO (0.43) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL13428306 | 0.85 | FTO (0.35) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL3626595 | 0.85 | FTO (0.43) | KDM4EMEN1USP2CYP3A4MAPT | |
| SCHEMBL18258300 | 0.84 | KDM4E (0.34) | KDM4EMEN1USP2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433473-B1 | Dyeing composition containing a specific polycationic direct dye, method of dyeing, use and multicompartment device | OREAL (FR) | 2010-11-17 | — | — | EP | claimed |
| US-7241319-B2 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2007-07-10 | — | — | US | claimed |
| US-20040194229-A1 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| US-7241319-B2 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-20040194229-A1 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040194229-A1 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | COL14A1, COL1A1, KRT18 | KDM4E 1385/4885MEN1 737/4885USP2 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.