Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | PIEZO1 | Q92508 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.31 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3104128 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL5281859 | 0.82 | MEN1 (0.49) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL4398070 | 0.81 | CDC7 (0.39) | ALDH1A1PIEZO1 | |
| SCHEMBL4385761 | 0.77 | CXCR2 (0.40) | — | |
| SCHEMBL4396806 | 0.77 | NPC1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4436678 | 0.74 | — | — | |
| SCHEMBL3381068 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL3381582 | 0.73 | PIEZO1 (0.35) | PIEZO1 | |
| SCHEMBL4284684 | 0.72 | — | — | |
| SCHEMBL20855351 | 0.72 | RAB9A (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799657-B1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LTD (GB) | 2009-12-02 | — | — | EP | disclosed |
| US-7465805-B2 | Isoxazoline derivatives and their use as herbicides | SYNGENTA LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| US-20080051287-A1 | Isoxazoline Derivatives and Their Use as Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-02-28 | — | — | US | disclosed |
| EP-1799657-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037945-A1 | ISOXAZOLINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051287-A1 | Isoxazoline Derivatives and Their Use as Herbicides | CYP4X1, CYP3A7, CYP4Z1 | SLC6A2 2006/4885SLC6A4 1470/4885P2RX7 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.