SCHEMBL3384231

SCHEMBL3384231

c1ccc2c(c1)c1ccccc1n1nccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
HTR3A P46098 1/20 0.42
HTR3D Q70Z44 1/20 0.42
HTR3C Q8WXA8 1/20 0.42
GPR3 P46089 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
SLC6A2 P23975 2/20 0.39
KDM4E B2RXH2 3/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAOA P21397 4/20 0.39
MAOB P27338 4/20 0.39
ACHE P22303 1/20 0.39
CYP19A1 P11511 1/20 0.35
POLB P06746 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
BACE1 P56817 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15349388 0.81 HTR3E (0.38) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL16921374 0.77 ALKBH5 (0.51) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL16863653 0.74 TDP1 (0.43) CYP1A2CYP2C19KDM4EPOLBNPC1
SCHEMBL16871672 0.73 KDM4E (0.47) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL16871419 0.72 CDK5 (0.36) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL9138426 0.70 HTR3E (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL362986 0.70 HTR3E (0.56) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29792929 0.70 NPC1 (0.41) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL10099727 0.70 HTR3E (0.52) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL8797846 0.69 ADORA3 (0.54) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11145829-B2 Organic electroluminescent device, organic electroluminescent display device including the same, and organometallic compound for organic electroluminescent device SAMSUNG DISPLAY CO., LTD. 2021-10-12 US disclosed
US-20190245154-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-08 US disclosed
US-8987451-B2 Synthesis of cyclometallated platinum(II) complexes UNIVERSAL DISPLAY CORPORATION (US) 2015-03-24 US disclosed
US-20150076466-A1 BLUE LUMINESCENT COMPOUNDS E. I. DUPONT DE NEMOURS AND COMPANY 2015-03-19 US disclosed
US-20150076466-A1 BLUE LUMINESCENT COMPOUNDS E. I. DUPONT DE NEMOURS AND COMPANY 2015-03-19 US disclosed
US-20150076466-A1 BLUE LUMINESCENT COMPOUNDS E. I. DUPONT DE NEMOURS AND COMPANY 2015-03-19 US disclosed
EP-2841442-A1 BLUE LUMINESCENT COMPOUNDS E. I. Du Pont de Nemours and Company (US) 2015-03-04 EP disclosed
WO-2013163022-A1 BLUE LUMINESCENT COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-10-31 WO disclosed
WO-2013163022-A1 BLUE LUMINESCENT COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-10-31 WO disclosed
US-20130172561-A1 SYNTHESIS OF CYCLOMETALLATED PLATINUM(II) COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2013-07-04 US disclosed
JP-2010215759-A ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY, LIGHTING DEVICE, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT KONICA MINOLTA HOLDINGS INC 2010-09-30 JP disclosed
EP-1494673-B1 COMPOUNDS HAVING UNIQUE CB1 RECEPTOR BINDING SELECTIVITY AND METHODS FOR THEIR PRODUCTION AND USE RES TRIANGLE INST (US) 2008-08-13 EP disclosed
EP-1494673-A4 COMPOUNDS HAVING UNIQUE CB1 RECEPTOR BINDING SELECTIVITY AND METHODS FOR THEIR PRODUCTION AND USE RES TRIANGLE INST (US) 2006-01-18 EP disclosed
EP-1494673-A1 COMPOUNDS HAVING UNIQUE CB1 RECEPTOR BINDING SELECTIVITY AND METHODS FOR THEIR PRODUCTION AND USE RESEARCH TRIANGLE INSTITUTE (US) 2005-01-12 EP disclosed
US-6825209-B2 AN AMIDE DERIVATIVE USED AS CANNABINOID ANTAGONIST FOR THE TREATMENT OF OBESITY, SCHIZOPHRENIA, MEMORY DYSFUNCTION AND MARIJUANA ABUSE RESEARCH TRIANGLE INSTITUTE 2004-11-30 US disclosed
WO-2003088968-A1 COMPOUNDS HAVING UNIQUE CB1 RECEPTOR BINDING SELECTIVITY AND METHODS FOR THEIR PRODUCTION AND USE RESEARCH TRIANGLE INSTITUTE (US) 2003-10-30 WO disclosed
US-20030199536-A1 Compounds having unique CB1 receptor binding selectivity and methods for their production and use RESEARCH TRIANGLE INSTITUTE (US) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199536-A1 Compounds having unique CB1 receptor binding selectivity and methods for their production and use CNR1, CNR2, GPR18 HTR3E 301/4885HTR3B 45/4885HTR3A 64/4885
US-11145829-B2 Organic electroluminescent device, organic electroluminescent display device including the same, and organometallic compound for organic electroluminescent device L1CAM, OCIAD1, USE1 HTR3E 3852/4885HTR3B 3960/4885HTR3A 3562/4885
US-20190245154-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE INCLUDING THE SAME, AND ORGANOMETALLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE L1CAM, OCIAD1, USE1 HTR3E 3852/4885HTR3B 3960/4885HTR3A 3562/4885
US-20130172561-A1 SYNTHESIS OF CYCLOMETALLATED PLATINUM(II) COMPLEXES OCIAD2, OCIAD1, PDCD2L HTR3E 4178/4885HTR3B 2650/4885HTR3A 3372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.