Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.48 |
| ▸ | CES1 | P23141 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16080776 | 0.87 | MAPT (0.47) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL476901 | 0.84 | MAPT (0.44) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL1850995 | 0.83 | MAPT (0.49) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL28475093 | 0.83 | MAPT (0.46) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL867792 | 0.81 | LMNA (0.55) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL2980323 | 0.81 | LMNA (0.55) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL2982475 | 0.81 | LMNA (0.55) | MAPTALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL16046636 | 0.81 | LMNA (0.49) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL16044452 | 0.81 | LMNA (0.49) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL7637265 | 0.81 | CES2 (0.52) | CES2CES1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661901-B1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | EASTMAN CHEM CO (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-110997605-B | Synthesis of diols by transfer hydrogenation of alpha-functionalized esters with alcohols | 伊士曼化工公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-3661901-A1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | Eastman Chemical Company (US) | 2020-06-10 | — | — | EP | disclosed |
| CN-110997605-A | Synthesis of diols by transfer hydrogenation of α -functionalized esters with alcohols | 伊士曼化工公司 | 2020-04-10 | — | — | CN | disclosed |
| US-10266467-B2 | Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols | EASTMAN CHEMICAL COMPANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20190039978-A1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | EASTMAN CHEMICAL COMPANY (US) | 2019-02-07 | — | — | US | disclosed |
| WO-2019027948-A1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | EASTMAN CHEMICAL COMPANY (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20170266103-A1 | MICROCAPSULES CONTAINING A GAS-GENERATING PHOTOLABILE POLYMER AND USES THEREOF | FIRMENICH SA (CH) | 2017-09-21 | — | — | US | disclosed |
| EP-1327633-B1 | Crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo(5.5.0.0.59O3,11)-dodecane | ALLIANT TECHSYSTEMS INC (US) | 2010-12-15 | — | — | EP | disclosed |
| US-7288648-B2 | High temperature crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,903,11]-dodecane | ALLIANT TECHSYSTEMS INC. (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070225493-A1 | Combining CL-20 organic solvent, nonsolvent to form a crystallization solution; saturating the crystallization solution;heating the crystallization solution to a temperature of from about 71 degrees C. to about 94 degrees C.; removing the at least one organic solvent and nonsolvent; separation | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2007-09-27 | — | — | US | disclosed |
| US-6992185-B2 | Crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,903,11]-dodecane | ALLIANT TECHSYSTEMS INC. (US) | 2006-01-31 | — | — | US | disclosed |
| EP-1327633-A1 | Crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo(5.5.0.0.59O3,11)-dodecane | ALLIANT TECHSYSTEMS INC. (US) | 2003-07-16 | — | — | EP | disclosed |
| US-20030130503-A1 | Crystallization of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazatetracyclo[5.5.0.05,903,11]-dodecane | NORTHROP GRUMMAN SYSTEMS CORPORATION | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190039978-A1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | ADH1A, ADH1C, ADH5 | CES2 366/4885CES1 214/4885MAPT 2064/4885 |
| US-20170266103-A1 | MICROCAPSULES CONTAINING A GAS-GENERATING PHOTOLABILE POLYMER AND USES THEREOF | TNF, PHGDH, PHYKPL | CES2 1351/4885CES1 543/4885MAPT 682/4885 |
| US-10266467-B2 | Synthesis of glycols via transfer hydrogenation of alpha-functional esters with alcohols | ADH1A, ADH1C, ADH5 | CES2 366/4885CES1 214/4885MAPT 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.