Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 10/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385496 | 0.91 | KDR (0.50) | WNT3AKDRFGFR3MEN1RAB9A | |
| SCHEMBL3385509 | 0.89 | WNT3A (0.49) | WNT3AKDRFGFR3RET | |
| SCHEMBL3383499 | 0.88 | KDR (0.46) | WNT3AKDRFGFR3 | |
| SCHEMBL3384812 | 0.88 | KDR (0.45) | WNT3AKDRFGFR3 | |
| SCHEMBL3382504 | 0.88 | KDR (0.47) | WNT3AKDRFGFR3 | |
| SCHEMBL3385467 | 0.87 | KDR (0.49) | WNT3AKDRFGFR3MEN1RAB9A | |
| SCHEMBL3385345 | 0.85 | RET (0.60) | WNT3AKDRFGFR3RET | |
| SCHEMBL3417117 | 0.83 | WNT3A (0.49) | WNT3AKDRFGFR3 | |
| SCHEMBL3385413 | 0.82 | RORC (0.48) | WNT3AKDRFGFR3MEN1RAB9A | |
| SCHEMBL3385380 | 0.82 | KDR (0.47) | WNT3AKDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |