Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL3922241 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL30634898 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27683384 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL4506082 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27627922 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27622258 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL6765309 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL2937671 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL7030044 | 0.95 | ALDH1A1 (0.70) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL29098715 | 0.95 | ALDH1A1 (0.70) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101405034-B | Liquid deodorant composition and method of deodorization | TAKASAGO PERFUMERY CO LTD | 2013-03-20 | — | — | CN | claimed |
| US-8333957-B2 | Liquid deodorant composition and deodorizing method | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-12-18 | — | — | US | claimed |
| US-20090092571-A1 | LIQUID DEODORANT COMPOSITION AND DEODORIZING METHOD | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-04-09 | — | — | US | claimed |
| CN-101405034-A | Liquid deodorant composition and method of deodorization | TAKASAGO PERFUMERY CO LTD (JP) | 2009-04-08 | — | — | CN | claimed |
| EP-2042198-A1 | LIQUID DEODORANT COMPOSITION AND METHOD OF DEODORIZING | Takasago International Corporation (JP) | 2009-04-01 | — | — | EP | claimed |
| CN-101405034-B | Liquid deodorant composition and method of deodorization | TAKASAGO PERFUMERY CO LTD | 2013-03-20 | — | — | CN | disclosed |
| US-8333957-B2 | Liquid deodorant composition and deodorizing method | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100074971-A1 | DOUBLE PREPARATION TYPE ANTIOXIDANT COMPOSITION AND ANTIOXIDATION PRODUCT COMPRISING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20090092571-A1 | LIQUID DEODORANT COMPOSITION AND DEODORIZING METHOD | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| CN-101405034-A | Liquid deodorant composition and method of deodorization | TAKASAGO PERFUMERY CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| EP-2042198-A1 | LIQUID DEODORANT COMPOSITION AND METHOD OF DEODORIZING | Takasago International Corporation (JP) | 2009-04-01 | — | — | EP | disclosed |