Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL4506082 | 1.00 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL8830995 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27683384 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL3922241 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL30634898 | 0.98 | ALDH1A1 (0.67) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL28351574 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL6765309 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27622258 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL3385754 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 | |
| Phthalic Acid SCHEMBL27627922 | 0.95 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12350460-B2 | Electro-responsive silk fibroin material, electro-responsive silk fibroin microneedle, insulin microneedle patch having electro-responsive silk fibroin and preparation method therefor, and transdermal drug delivery device | Pharsun Medical Biotechnics (Shanghai) Co., Ltd. (CN) | 2025-07-08 | — | — | US | claimed |
| CN-120060412-A | Resistant starch and preparation method thereof | 首都医科大学附属北京儿童医院 | 2025-05-30 | — | — | CN | claimed |
| CN-119978826-A | Composite stabilizer of colloid Jin Tiwai diagnostic reagent and preparation method thereof | 湖南杰菲特生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-118224917-B | System and method for inhibiting running corrosion of condenser | 西安热工研究院有限公司 | 2025-04-15 | — | — | CN | claimed |
| WO-2025011543-A1 | DRUG NANO MULTI-LEVEL STRUCTURE COATING AND PREPARATION METHOD THEREFOR | 四川大学华西医院 | 2025-01-16 | — | — | WO | claimed |
| WO-2025011542-A1 | DRUG STRUCTURAL COATING HAVING SUPER-HYDROPHOBIC PROPERTY AND PREPARATION METHOD THEREFOR | 四川大学华西医院 | 2025-01-16 | — | — | WO | claimed |
| WO-2025011541-A1 | DRUG MICELLE OF CORE-SHELL-SHELL STRUCTURE HAVING TARGETING FUNCTION AND PREPARATION METHOD THEREFOR | 四川大学华西医院 | 2025-01-16 | — | — | WO | claimed |
| CN-119285792-A | FAP-targeted CAR-macrophage with enhanced cytoburied effect and preparation method and application thereof | 山东大学齐鲁医院 | 2025-01-10 | — | — | CN | claimed |
| US-20250001153-A1 | ELECTRO-RESPONSIVE SILK FIBROIN MATERIAL, ELECTRO-RESPONSIVE SILK FIBROIN MICRONEEDLE, INSULIN MICRONEEDLE PATCH HAVING ELECTRO-RESPONSIVE SILK FIBROIN AND PREPARATION METHOD THEREFOR, AND TRANSDERMAL DRUG DELIVERY DEVICE | Pharsun Medical Biotechnics (Shanghai) Co., Ltd. (CN) | 2025-01-02 | — | — | US | claimed |
| CN-119061112-A | Alpha-L-fucosidase detection reagent or kit and preparation method thereof | 中生北控生物科技股份有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-108174855-A | A kind of non-corrosive chlorine-containing disinfecting effervescent tablet | 北京长江脉医药科技有限责任公司 | 2018-06-19 | — | — | CN | claimed |
| CN-107441038-A | A kind of ornithine aspartate injection and preparation method thereof | 济南康和医药科技有限公司 | 2017-12-08 | — | — | CN | claimed |
| CN-103908513-B | The extracting method of shinyleaf yellowhorn fruit shell total saponins | NO. 210 HOSPITAL, PLA (CN) | 2016-01-27 | — | — | CN | claimed |
| CN-104971200-A | Tannic acid pH-stable hemorrhoid gel and preparation method thereof | ZHEJIANG HONGYU MEDICAL COMMODITY CO LTD | 2015-10-14 | — | — | CN | claimed |
| CN-103908513-A | Method for extracting total saponins of xanthoceras sorbifolia shell | NO 210 HOSPITAL PLA | 2014-07-09 | — | — | CN | claimed |
| CN-103250860-A | Horseradish gum and preparation method thereof | UNIV CHENGDU | 2013-08-21 | — | — | CN | claimed |
| CN-101555506-A | Enzymolysis method of wood fiber raw materials | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-10-14 | — | — | CN | claimed |
| CN-1110567-C | Preparation of deoxynucleoside triphosphate | BEIJING TAIGONG BIOLOG TECHNOL (CN) | 2003-06-04 | — | — | CN | claimed |
| CN-1269422-A | Method for preparing deoxyribonucleoside triphosphate | GUO HUANFANG (CN) | 2000-10-11 | — | — | CN | claimed |
| US-5654156-A | PREPARING REAGENT COMPRISING LIPOSOMES CONTAINING ANTIGEN OR ANTIBODY WHICH BINDS ANALYTE TO BE MEASURED, ENCAPSULATING MARKER THEREIN, ACIDIFYING SAMPLE, CONTACTING SAMPLE WITH REAGENT, MEASURING AMOUNT OF DETECTABLE MARKER RELEASED | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250001153-A1 | ELECTRO-RESPONSIVE SILK FIBROIN MATERIAL, ELECTRO-RESPONSIVE SILK FIBROIN MICRONEEDLE, INSULIN MICRONEEDLE PATCH HAVING ELECTRO-RESPONSIVE SILK FIBROIN AND PREPARATION METHOD THEREFOR, AND TRANSDERMAL DRUG DELIVERY DEVICE | MSTN, NOTUM, DSTN | ALDH1A1 2926/4885ALOX15 2318/4885KDM4E 722/4885 |
| US-12350460-B2 | Electro-responsive silk fibroin material, electro-responsive silk fibroin microneedle, insulin microneedle patch having electro-responsive silk fibroin and preparation method therefor, and transdermal drug delivery device | MSTN, MYOF, DSTN | ALDH1A1 3238/4885ALOX15 3215/4885KDM4E 1645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.