SCHEMBL338710

SCHEMBL338710

N#C[CH]c1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.41
ERBB2 P04626 1/20 0.39
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
EGFR P00533 1/20 0.36
IGF1R P08069 1/20 0.36
IGF2R P11717 1/20 0.36
TSHR P16473 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 2/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34
LTA4H P09960 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BCAT2 O15382 1/20 0.33
BCAT1 P54687 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11036204 0.97 TTR (0.39) TTRERBB2HTR2ASLC6A4EGFR
SCHEMBL10549001 0.88 ALDH1A1 (0.38) HTR2ASLC6A4CYP1A2CYP3A4CYP2C19
SCHEMBL10550056 0.87 SLC6A2 (0.39) SLC6A4LMNA
SCHEMBL10545050 0.86 HTR2A (0.40) HTR2ASLC6A4CYP1A2CYP2C9CYP2C19
SCHEMBL10548556 0.86 SLC6A2 (0.36) SLC6A4KMT2AL3MBTL1PARP10
SCHEMBL10548149 0.85 AR (0.42) HTR2ASLC6A4CYP1A2CYP2C9CYP2C19
SCHEMBL10549379 0.85 NFE2L2 (0.42) TTRTSHRCYP1A2CYP3A4GAA
SCHEMBL28967893 0.85 FDPS (0.43) TTRERBB2HTR2ASLC6A4EGFR
SCHEMBL10547571 0.85 AR (0.41) HTR2ASLC6A4LMNA
SCHEMBL10549574 0.85 TUBB4A (0.33) SLC6A4NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325385-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2017-10-04 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
EP-1261255-B1 METHOD FOR FIGHTING AGAINST ARTHROPODS DESTRUCTIVE OF CROPS AND COMPOSITION THEREFOR BASF AGRO B V ARNHEM NL WAEDEN (CH) 2007-06-06 EP claimed
EP-1322166-B1 SEED TREATMENT WITH COMBINATIONS OF INSECTICIDES MONSANTO TECHNOLOGY LLC (US) 2007-04-25 EP claimed
EP-0988788-B1 INSECTICIDE/MITICIDE COMPOSITION BASF AG (DE) 2003-12-03 EP claimed
US-20030187029-A1 Method for fighting against arthropods destructive of crops and compositions therefor BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) 2003-10-02 US claimed
JP-2003525885-A 2003-09-02 JP claimed
US-6514510-B1 Insecticidal and miticidal compositions BASF AKTIENGESELLSCHAFT (DE) 2003-02-04 US claimed
EP-1261255-A1 METHOD FOR FIGHTING AGAINST ARTHROPODS DESTRUCTIVE OF CROPS AND COMPOSITION THEREFOR AVENTIS CROPSCIENCE S.A. (FR) 2002-12-04 EP claimed
WO-2001065941-A1 METHOD FOR FIGHTING AGAINST ARTHROPODS DESTRUCTIVE OF CROPS AND COMPOSITION THEREFOR AVENTIS CROPSCIENCE S.A. (FR) 2001-09-13 WO claimed
US-4569928-A UNSATURATED CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES ROUSSEL UCLAF (FR) 1986-02-11 US claimed
US-4565822-A INSECTICIDES, NEMATOCIDES, MITICIDES ROUSSEL UCLAF (FR) 1986-01-21 US claimed
EP-0107570-B1 CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES SUBSTITUTED AT POSITION 3 BY A SUBSTITUTED VINYL GROUP, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1986-01-15 EP claimed
US-4556666-A INSECTICIDES ROUSSEL UCLAF (FR) 1985-12-03 US claimed
EP-0093664-B1 ESTER OF CYCLOPROPANECARBOXYLIC ACID AND (S)-CYANO-(4-FLUORO-3-PHENOXYPHENYL)-METHYL ALCOHOL, ITS PREPARATION, ITS USE IN COMBATING PARASITES AND COMPOSITIONS CONTAINING IT ROUSSEL-UCLAF (FR) 1985-09-11 EP claimed
US-4537897-A PESTICIDES ROUSSEL UCLAF (FR) 1985-08-27 US claimed
EP-0109909-B1 DERIVATIVES OF 2,2-DIMETHYL-3-(2-FLUORO-3-OXO-3-(1,1-DIMETHYLETHOXY)-1-PROPENYL)CYCLOPROPANECARBOXYLIC ACID ROUSSEL-UCLAF (FR) 1985-08-21 EP claimed
US-4489093-A Insecticidal esters ROUSSEL UCLAF (FR) 1984-12-18 US claimed
US-4478850-A DESTICIDES, NEMATOCIDES, MITICIDES, AND INSECTICIDES ROUSSEL UCLAF (FR) 1984-10-23 US claimed
EP-0025542-B1 (+/-)-(ALPHA-CYANO-3-PHENOXY-4-FLUORO-BENZYLIC)ESTERS OF (+/-)-TRANS-3-(E,Z-2-CHLORO-2-(4-CHLORO-PHENYL)-VINYL)-2,2-DIMETHYL-CYCLOPROPANE CARBOXYLIC ACID, THEIR E AND Z ISOMERS, A PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS ECTOPARASITICIDES BAYER AG (DE) 1983-02-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187029-A1 Method for fighting against arthropods destructive of crops and compositions therefor WAPL, AGL, OSGEP TTR 1546/4885ERBB2 4867/4885HTR2A 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.