Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239331 | 0.88 | IDO1 (0.44) | HTR2AIDO1AOC3MAOAMAOB | |
| SCHEMBL11655201 | 0.83 | ALDH1A1 (0.34) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL837631 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL19927446 | 0.82 | IDO1 (0.45) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL18389643 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL2510929 | 0.80 | TP53 (0.39) | ALDH1A1TAAR1TDP1LOXL2IDO1 | |
| SCHEMBL3342114 | 0.79 | TP53 (0.39) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL17519998 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL8382117 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL7749434 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15ALOX12CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187266-B1 | SOLID SILICONE DEFOAMING AGENT AND METHOD FOR ITS PRODUCTION | Toray Silicone Company Limited (JP) | 1988-03-16 | — | — | EP | claimed |
| US-4613640-A | HYDROCARBON POLYMER, MINERAL OIL, POLYSILOXANES, MEDICAL EQUIPMENT | MEDICAL RESEARCH ASSOCIATES, LTD. #2 (US) | 1986-09-23 | — | — | US | claimed |
| US-4016328-A | SILICONE RESIN, SILICONE GUM, 2,4-DICHLOROBENZOYL PEROXIDE AS CURING AGENT | GENERAL ELECTRIC COMPANY (US) | 1977-04-05 | — | — | US | claimed |
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | ABCR LABORATORIOS, S.L. (ES) | 2023-10-03 | — | — | US | disclosed |
| US-20200332149-A1 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | ABCR LABORATORIOS, S.L. (ES) | 2020-10-22 | — | — | US | disclosed |
| EP-3543304-B1 | ORGANOFUNCTIONAL SILOXANES, METHOD FOR ITS PREPARATION AND USE FOR THE TREATMENT OF FILLERS AND SURFACES | ABCR LABORATORIOS S L (ES) | 2020-08-05 | — | — | EP | disclosed |
| WO-2019180285-A2 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | ABCR LABORATORIOS, S.L. (ES) | 2019-09-26 | — | — | WO | disclosed |
| EP-3543304-A1 | ORGANOFUNCTIONAL SILOXANES, METHOD FOR ITS PREPARATION AND USE FOR THE TREATMENT OF FILLERS AND SURFACES | ABCR Laboratorios, S.L. (ES) | 2019-09-25 | — | — | EP | disclosed |
| US-8097602-B1 | Method of treating body insect infestation | HOST PHARMACEUTICALS, LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-6150441-A | A ONE-PACK SEALANT COMPRISING AN ADDITION POLYMER, A CURING AGENT HAVING AT LEAST TWO HYDROSILYL GROUPS IN ITS MOLECULE, A HYDROSILYLATION CATALYST AND A TACKIFIER; BINDING GLASS PLATES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-11-21 | — | — | US | disclosed |
| US-6101636-A | Sculptured helmet ornamentation | WILLIAMS MARIX (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0737720-A1 | Organosiloxane compositions exhibiting increased penetration into porous substrates | DOW CORNING CORPORATION (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5563197-A | HOMOGENEITY THIXOTROPIC LIQUID, PASTE OR GEL; BLENDING | DOW CORNING CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5563210-A | HOMOGENEITY THIXOTROPIC LIQUID, PASTE OR GEL; BLENDING;MOISTURE CURABLE | DOW CORNING CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0731142-A2 | Thixotropic organosiloxane compositions | DOW CORNING CORPORATION (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5516832-A | OF A POLYSILOXANE GUM, A REINFORCING FILLER, A POLYBUTYLENE AND A HYDROXY-TERMINATED POLYSILOXANE | DOW CORNING CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0710704-A2 | Curable silicone rubber composition | DOW CORNING CORPORATION (US) | 1996-05-08 | — | — | EP | disclosed |
| EP-0583775-A2 | Slipping layer binder for dye-donor element used in thermal dye transfer | EASTMAN KODAK COMPANY (US) | 1994-02-23 | — | — | EP | disclosed |
| US-5240899-A | Aminoalkyl(dialkysilyl)-terminated polydialkylsiloxane, polyvinyl acetal or formal | EASTMAN KODAK COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
| US-4656221-A | SOLVENT-FREE POLYSILOXANE COATINGS; RADIATION TRANSPARENT FOR USE ON COLORLESS BEVERAGE BOTTLES | TOSHIBA SILICONE CO., LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200332149-A1 | ORGANOFUNCTIONAL SILOXANES, PROCESS FOR PREPARING SAME AND THEIR USE FOR THE TREATMENT OF FILLINGS AND SURFACES | FDFT1, DBF4, IPO4 | ALDH1A1 523/4885HPGD 603/4885ALOX15 350/4885 |
| US-11773289-B2 | Organofunctional siloxanes, process for preparing same and their use for the treatment of fillings and surfaces | FDFT1, DBF4, IPO4 | ALDH1A1 523/4885HPGD 603/4885ALOX15 350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.