Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204575 | 0.76 | CYP2C19 (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL200578 | 0.75 | CYP2C19 (0.36) | SMN1; SMN2ALDH1A1HPGDMAPK1EPHX2 | |
| SCHEMBL5360193 | 0.73 | ELANE (0.35) | SMN1; SMN2ALDH1A1HPGDMAPK1EPHX2 | |
| SCHEMBL5366311 | 0.72 | CYP2D6 (0.34) | SMN1; SMN2ALDH1A1HPGDMAPK1EPHX2 | |
| SCHEMBL5836998 | 0.72 | EPHX2 (0.34) | ALDH1A1EPHX2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL32689139 | 0.71 | EPHX2 (0.38) | ALDH1A1MAPK1EPHX2EPHX1CYP2D6 | |
| SCHEMBL5837477 | 0.71 | CYP2D6 (0.33) | ALDH1A1HPGDEPHX2CYP2D6CYP2C19 | |
| SCHEMBL5837771 | 0.71 | EPHX2 (0.36) | ALDH1A1EPHX2CYP2D6CYP2C19MEN1 | |
| SCHEMBL533667 | 0.71 | EPHX2 (0.62) | EPHX2L3MBTL1 | |
| SCHEMBL30061004 | 0.70 | EPHX1 (0.41) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1621608-B1 | NOVEL BACTERIA CAPABLE OF BREAKING URETHANE BOND | JAPAN SCIENCE & TECH AGENCY (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-7547537-B2 | Urethane-bond-degrading bacteria | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20070099285-A1 | Novel urethane-bond-degrading bacteria | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1621608-A1 | NOVEL FUNGUS CAPABLE OF BREAKING URETHANE BOND | Japan Science and Technology Agency (JP) | 2006-02-01 | — | — | EP | disclosed |