SCHEMBL3389158

SCHEMBL3389158

FC(F)(F)CCC=CCCCCC(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 1/20 0.41
ALOX5 P09917 1/20 0.39
ACLY P53396 1/20 0.37
FAAH O00519 4/20 0.32
CES1 P23141 2/20 0.32
PLA2G4A P47712 2/20 0.32
ALDH1A1 P00352 1/20 0.31
PLA2G4B P0C869 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
MGLL Q99685 1/20 0.31
PLA2G4C Q9UP65 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20994190 0.85
SCHEMBL12476456 0.82 OXER1 (0.32) OXER1ALOX5PLA2G4A
SCHEMBL1818263 0.82 FAAH (0.50) FAAHCES1PLA2G4AALDH1A1PLA2G4B
SCHEMBL1818265 0.82 FAAH (0.50) FAAHCES1PLA2G4AALDH1A1PLA2G4B
SCHEMBL12476453 0.82 OXER1 (0.32) OXER1ALOX5PLA2G4A
SCHEMBL12477607 0.82 OXER1 (0.38) OXER1ALOX5ACLYPLA2G4A
SCHEMBL12477608 0.82 OXER1 (0.38) OXER1ALOX5ACLYPLA2G4A
SCHEMBL14931773 0.82 ALDH1A1 (0.38) OXER1ALOX5ACLYFAAHCES1
SCHEMBL1428312 0.82 FAAH (0.41) OXER1ALOX5ACLYFAAHCES1
SCHEMBL11254804 0.80 FAAH (0.32) OXER1ACLYFAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF THE CHEMOURS COMPANY FC, LLC (US) 2021-07-08 US disclosed
US-9540557-B2 Compositions comprising fluoroolefins and uses thereof THE CHEMOURS COMPANY FC, LLC (US) 2017-01-10 US disclosed
US-20150068227-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2015-03-12 US disclosed
US-20100132387-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-03 US disclosed
US-20100127208-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100127208-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 OXER1 4152/4885ALOX5 761/4885ACLY 2728/4885
US-20210207014-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 OXER1 4152/4885ALOX5 761/4885ACLY 2728/4885
US-20100132387-A1 COMPOSITIONS COMPRISING FLUOROOLEFINS AND USES THEREOF GFPT1, PFAS, TRMT1 OXER1 4152/4885ALOX5 761/4885ACLY 2728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.