Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 4/20 | 0.35 |
| ▸ | GRK6 | P43250 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3389367 | 0.86 | ALDH1A1 (0.45) | CA2CA12CA1CA4CA7 | |
| SCHEMBL3392363 | 0.81 | KDM4E (0.43) | CA2CA12CA1CA4CA7 | |
| SCHEMBL3395053 | 0.81 | ALDH1A1 (0.48) | CA2CA12CA1CA4CA7 | |
| SCHEMBL3391447 | 0.79 | MAOB (0.44) | ALDH1A1CYP2C9HPGD | |
| Ether SCHEMBL6234273 | 0.78 | ALDH1A1 (0.42) | CA2CA12CA1CA4CA7 | |
| SCHEMBL3393388 | 0.76 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL3395055 | 0.73 | AKR1C2 (0.43) | ALDH1A1CYP2C9HPGDGRK6LCK | |
| SCHEMBL3391703 | 0.72 | KDM4E (0.31) | LMNAHPGDTSHRNFKB1PMP22 | |
| SCHEMBL14338091 | 0.70 | ALDH1A1 (0.47) | CA2CA12CA1CA4CA7 | |
| SCHEMBL13712963 | 0.70 | ALDH1A1 (0.44) | CA12CA9ALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CA2 4395/4885CA12 4101/4885CA1 4367/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | CA2 4484/4885CA12 4557/4885CA1 4607/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | CA2 4440/4885CA12 4493/4885CA1 4765/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CA2 4395/4885CA12 4101/4885CA1 4367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.