Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394904 | 0.93 | LMNA (0.35) | LMNA | |
| SCHEMBL14019700 | 0.91 | LMNA (0.33) | LMNA | |
| SCHEMBL13008563 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL13108985 | 0.83 | EPHX1 (0.32) | — | |
| SCHEMBL13108984 | 0.82 | — | — | |
| SCHEMBL13108999 | 0.82 | LMNA (0.31) | LMNA | |
| SCHEMBL14019698 | 0.81 | ADAM17 (0.39) | — | |
| SCHEMBL13001800 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL13108974 | 0.81 | POLB (0.32) | LMNA | |
| SCHEMBL4609091 | 0.80 | POLB (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | IVOCLAR VIVADENT AG (LI) | 2021-10-05 | — | — | US | disclosed |
| US-10660825-B2 | — | — | 2020-05-26 | — | — | US | disclosed |
| US-20190167533-A1 | DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2019-06-06 | — | — | US | disclosed |
| US-20180036209-A1 | Dental Materials Based on Monofunctional Vinylcyclopropane Derivatives | IVOCLAR VIVADENT AG (LI) | 2018-02-08 | — | — | US | disclosed |
| EP-1688125-B1 | Composition comprising polymerisable cyclopropylacrylates | IVOCLAR VIVADENT AG (LI) | 2010-12-29 | — | — | EP | disclosed |
| EP-1688125-B1 | Composition comprising polymerisable cyclopropylacrylates | IVOCLAR VIVADENT AG (LI) | 2010-12-29 | — | — | EP | disclosed |
| US-7816476-B2 | Polymerizable cyclopropyl acrylates | IVOCLAR VIVADENT AG (LI) | 2010-10-19 | — | — | US | disclosed |
| US-7816476-B2 | Polymerizable cyclopropyl acrylates | IVOCLAR VIVADENT AG (LI) | 2010-10-19 | — | — | US | disclosed |
| EP-1688125-A1 | Polymerisable cyclopropylacrylates | Ivoclar Vivadent AG (LI) | 2006-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036209-A1 | Dental Materials Based on Monofunctional Vinylcyclopropane Derivatives | HVCN1, RAD51, HYOU1 | LMNA 770/4885 |
| US-20190167533-A1 | DENTAL MATERIALS BASED ON URETHANE-GROUP-CONTAINING VINYLCYCLOPROPANE DERIVATIVES | RAD51, CBR1, DECR1 | LMNA 1045/4885 |
| US-11135136-B2 | Dental materials based on urethane-group-containing vinylcyclopropane derivatives | RAD51, CBR1, DECR1 | LMNA 1045/4885 |
| US-10660825-B2 | — | OXER1, CBR1, RAD51 | LMNA 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.