SCHEMBL3392233

SCHEMBL3392233

COc1ccc(-c2cc(CBr)n(C(=O)O)n2)nc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.39
SCD O00767 2/20 0.37
SCD5 Q86SK9 2/20 0.37
RXFP1 Q9HBX9 1/20 0.36
CBFB Q13951 1/20 0.35
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
NTRK1 P04629 1/20 0.34
ALDH1A1 P00352 3/20 0.33
GSK3B P49841 1/20 0.33
F2 P00734 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
TNKS O95271 1/20 0.33
P2RX7 Q99572 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SYK P43405 1/20 0.33
GRM5 P41594 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13425458 0.85 GPR119 (0.36) PTGER4SCDSCD5RXFP1CBFB
SCHEMBL13426579 0.69 ALDH1A1 (0.40) PTGER4SCDSCD5RXFP1ALDH1A1
SCHEMBL13425918 0.69 TRPA1 (0.38) GRM5
SCHEMBL30335253 0.69 CA12 (0.50) RXFP1CBFBALDH1A1TNKSNPC1
SCHEMBL3147993 0.69 CA12 (0.50) RXFP1CBFBALDH1A1TNKSNPC1
SCHEMBL3394445 0.69 ALPL (0.43) RXFP1ALDH1A1HPGDNPC1SMN1; SMN2
SCHEMBL13425944 0.68 CCR1 (0.44) ALDH1A1HPGDSYK
SCHEMBL13426455 0.68 HTT (0.45) ALDH1A1HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL3395670 0.68 SORT1 (0.32) ALDH1A1F2HPGDGRM5
SCHEMBL13425443 0.65 JAK2 (0.39) RXFP1ALDH1A1GLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046780-A2 ANTI VIRAL COMPOUNDS INSTITUT PASTEUR KOREA (KR) 2010-04-29 WO disclosed