Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788188 | 0.88 | — | — | |
| SCHEMBL7941245 | 0.77 | ACHE (0.30) | — | |
| SCHEMBL18137684 | 0.76 | — | — | |
| SCHEMBL19951089 | 0.76 | — | — | |
| SCHEMBL8742177 | 0.76 | — | — | |
| SCHEMBL10203452 | 0.75 | PPM1D (0.31) | — | |
| SCHEMBL16569783 | 0.74 | CA1 (0.33) | — | |
| SCHEMBL301584 | 0.74 | CA1 (0.33) | — | |
| SCHEMBL938204 | 0.72 | LRRK2 (0.33) | — | |
| SCHEMBL8753991 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368013-B1 | CYCLOHEXENONE DERIVATIVE FOR TREATING DIABETIC NEUROPATHY | MEIJI DAIRIES CORP (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-7838565-B2 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | MEIJI DAIRIES CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| EP-1368014-B1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | MEIJI DAIRIES CORP (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-6906107-B2 | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | MEIJI DAIRIES CORPORATION (JP) | 2005-06-14 | — | — | US | disclosed |
| US-20040132829-A1 | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-07-08 | — | — | US | disclosed |
| US-20040102527-A1 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-05-27 | — | — | US | disclosed |
| EP-1368014-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | Meiji Dairies Corporation (JP) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002066024-A1 | USE OF CYCLOHEXENONE DERIVATIVES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DYSURIA | MEIJI DAIRIES CORPORATION (JP) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132829-A1 | Use of cyclohexenone derivatives for the manufacture of a medicament in the treatment of dysuria | ADH1A, ADH1C, NDUFB7 | ESR2 1490/4885CYP19A1 684/4885 |
| US-20040102527-A1 | Use of cyclohexenone derivatives in the manufacture of a medicament for treating diabetic complications | GPR119, CYC1, CYP11B1 | ESR2 1373/4885CYP19A1 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.