Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393836 | 0.88 | GRK6 (0.33) | ALDH1A1HTTMEN1GAAKMT2A | |
| SCHEMBL3393835 | 0.88 | GRK6 (0.33) | ALDH1A1HTTMEN1GAAKMT2A | |
| SCHEMBL27649419 | 0.84 | LMNA (0.33) | ALDH1A1HTTMEN1GAAKMT2A | |
| SCHEMBL3391681 | 0.80 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTLMNA | |
| SCHEMBL1522711 | 0.77 | NPC1 (0.34) | HTTMEN1GAAKMT2AMAPT | |
| SCHEMBL15884036 | 0.74 | CYP1A2 (0.44) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL3393400 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MEN1GAAKMT2AMAPT | |
| SCHEMBL6686546 | 0.69 | CXCR2 (0.38) | ALDH1A1GAAMAPTLMNA | |
| SCHEMBL3391703 | 0.69 | KDM4E (0.31) | GAAMAPTLMNA | |
| SCHEMBL3389367 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | ALDH1A1 1434/4885HTT 4085/4885MEN1 4676/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | ALDH1A1 891/4885HTT 4340/4885MEN1 4453/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | ALDH1A1 1592/4885HTT 3990/4885MEN1 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.