Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 10/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13839983 | 0.81 | KDM4E (0.31) | ALDH1A1CYP3A4TDP1MAPTKDM4E | |
| SCHEMBL473606 | 0.80 | CHRNB2 (0.34) | ALDH1A1TSHRALOX15HSD17B10CYP3A4 | |
| SCHEMBL28787336 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TSHRALOX15HSD17B10SLC2A1 | |
| SCHEMBL194828 | 0.77 | CYP2A6 (0.52) | ALDH1A1TSHRALOX15HSD17B10SLC2A1 | |
| SCHEMBL13665344 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10SLC2A1 | |
| SCHEMBL12925273 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL274124 | 0.73 | CA1 (0.58) | ALDH1A1TSHRALOX15CYP2A6CYP3A4 | |
| SCHEMBL2536968 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10SLC2A1 | |
| SCHEMBL194091 | 0.73 | ACHE (0.48) | ALDH1A1TSHRCYP2A6CYP3A4TDP1 | |
| SCHEMBL13839981 | 0.72 | ESR1 (0.43) | ALDH1A1TSHRALOX15CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394153-B1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | UNIMATEC CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7812157-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20080227977-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. | 2008-09-18 | — | — | US | disclosed |
| US-7384995-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20070155868-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. | 2007-07-05 | — | — | US | disclosed |
| US-7199169-B2 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | UNIMATEC CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20040162368-A1 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | UNIMATEC CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1394153-A1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | Unimatec Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227977-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | TST, CTH, NACA | ALDH1A1 577/4885TSHR 3849/4885ALOX15 1959/4885 |
| US-20040162368-A1 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | TST, NACA, CTH | ALDH1A1 188/4885TSHR 4349/4885ALOX15 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.