Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8050878 | 0.76 | TSHR (0.30) | — | |
| SCHEMBL5610478 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL9662674 | 0.71 | CASP1 (0.32) | — | |
| SCHEMBL28366264 | 0.68 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL1500282 | 0.67 | — | — | |
| SCHEMBL10344679 | 0.67 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL7858703 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL252367 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL7262903 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL3397951 | 0.66 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087732-B2 | Nucleotides and analogs having photoremovable protecting groups | AFFYMETRIX, INC. (US) | 2006-08-08 | — | — | US | claimed |
| US-8247540-B2 | Caged nucleotides and oligonucleotides and their application | DEITERS ALEXANDER (US) | 2012-08-21 | — | — | US | disclosed |
| US-20100099159-A1 | CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION | DEITERS ALEXANDER | 2010-04-22 | — | — | US | disclosed |
| US-5874568-A | CAN BE USED IN STUDIES FOR ELUCIDATING THE MECHANISMS OF MUTATIONS AND REPAIR OF DNA, ALSO USEFUL AS A REAGENT FOR CLINICAL TESTS, SUCH AS PRODUCTION OF ANTIBODIES DETECTING DAMAGED DNA. | BIOMOLECULAR ENGINEERING RESEARCH INSTITUTE (JP) | 1999-02-23 | — | — | US | disclosed |
| EP-0787740-A2 | Coupling unit of (6-4)photoproduct, process for preparing the same, process for preparing oligonucleotide containing (6-4) photoproduct by using the same and process for preparing DNA containing (6-4) photoproduct by using the same | Biomolecular Engineering Research Institute (JP) | 1997-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099159-A1 | CAGED NUCLEOTIDES AND OLIGONUCLEOTIDES AND THEIR APPLICATION | RNGTT, NT5C3B, ADAR | ALDH1A1 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.