SCHEMBL339627

SCHEMBL339627

CCO[Si](OCC)(OCC)C(CNC(C)N)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.42
TAAR1 Q96RJ0 4/20 0.42
SLC6A2 P23975 2/20 0.42
MAOA P21397 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
CYP2A6 P11509 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
CYP2D6 P10635 1/20 0.40
EPHX1 P07099 1/20 0.37
SLC18A2 Q05940 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21060555 0.89 SIGMAR1 (0.41) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL37760 0.85 SIGMAR1 (0.44) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL21060572 0.84 SIGMAR1 (0.43) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL339626 0.79 SIGMAR1 (0.36) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL15514141 0.78 SIGMAR1 (0.43) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL614548 0.76 ALDH1A1 (0.43) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL2526801 0.75 TAAR1 (0.37) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL27791298 0.75 TAAR1 (0.37) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL2520766 0.75 ANPEP (0.43) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL2181964 0.74 TAAR1 (0.47) SIGMAR1TAAR1SLC6A2MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355811-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-11-09 US claimed
WO-2022067351-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2022-03-31 WO claimed
US-20150175812-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2015-06-25 US claimed
US-8343624-B2 Durable antireflective film 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-01 US claimed
US-20120135210-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2012-05-31 US claimed
WO-2012018290-A1 DISCRETE COATED NANOPARTICLES KEMPE MARIA (SE) 2012-02-09 WO claimed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US claimed
EP-2033020-A2 DURABLE ANTIREFLECTIVE FILM WITH SURFACE MODIFIED INORGANIC NANOPARTICLES 3M Innovative Properties Company (US) 2009-03-11 EP claimed
JP-4166581-B2 2008-10-15 JP claimed
US-20080064825-A1 BONDING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-03-13 US claimed
US-20060147723-A1 Optically transmissive, stain and ink repellent, durable, optical display, coating, applied to substrates of articles used in the computer, television, appliance, mobile phone, aerospace and automotive industries 3M INNOVATIVE PROPERTIES COMPANY 2006-07-06 US claimed
EP-1401927-B1 FLUOROPOLYMER BONDING 3M INNOVATIVE PROPERTIES CO (US) 2006-05-03 EP claimed
WO-2006019650-A1 BONDING COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-02-23 WO claimed
US-20050233150-A1 Bonding compositions 3M INNOVATIVE PROPERTIES COMPANY 2005-10-20 US claimed
US-20050208308-A1 Bonding compositions 3M INNOVATIVE PROPERTIES COMPANY 2005-09-22 US claimed
JP-2004536722-A 2004-12-09 JP claimed
US-20040197568-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2004-10-07 US claimed
EP-1401927-A2 FLOUROPOLYMER BONDING 3M Innovative Properties Company (US) 2004-03-31 EP claimed
US-20020197481-A1 Fluoropolymer bonding 3M INNOVATIVE PROPERTIES COMPANY 2002-12-26 US claimed
WO-2002094911-A2 FLOUROPOLYMER BONDING 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-11-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060147723-A1 Optically transmissive, stain and ink repellent, durable, optical display, coating, applied to substrates of articles used in the computer, television, appliance, mobile phone, aerospace and automotive industries PIR, MACF1, RAD54L SIGMAR1 1304/4885TAAR1 12/4885SLC6A2 2561/4885
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN SIGMAR1 673/4885TAAR1 4128/4885SLC6A2 3196/4885
US-20230355811-A1 COMPOSITIONS INCLUDING MAGNETIC NANOPARTICLES AND METHODS OF USING AND MAKING THE SAME CAPG, CD47, LMNB1 SIGMAR1 2576/4885TAAR1 4030/4885SLC6A2 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.