SCHEMBL3396448

SCHEMBL3396448

c1ccc2c(c1)Cc1c-2ccc2c1CCCC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
PNMT P11086 1/20 0.44
HPGD P15428 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
BCL2L1 Q07817 1/20 0.42
BAD Q92934 1/20 0.42
SRD5A2 P31213 1/20 0.40
MAOA P21397 2/20 0.38
CYP2A6 P11509 1/20 0.38
MAOB P27338 1/20 0.38
PGR P06401 1/20 0.38
CES1 P23141 1/20 0.38
KIF11 P52732 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23704623 0.98 PNMT (0.43) TSHRPNMTHPGDNPC1RAB9A
SCHEMBL29576506 0.96 PNMT (0.44) TSHRPNMTHPGDNPC1RAB9A
SCHEMBL22263591 0.83 PNMT (0.57) PNMTHPGDNPC1RAB9AALDH1A1
SCHEMBL30566335 0.81 ALDH1A1 (0.52) TSHRPNMTHPGDNPC1RAB9A
SCHEMBL8941775 0.81 CYP2A6 (0.47) TSHRHPGDL3MBTL1BCL2L1BAD
SCHEMBL28852797 0.77 TSHR (0.44) TSHRHPGDNPC1RAB9AALDH1A1
SCHEMBL4974372 0.77 BCL2L1 (0.60) TSHRHPGDALDH1A1KDM4ELMNA
SCHEMBL20402090 0.77 MAOA (0.56) PNMTHPGDNPC1RAB9AALDH1A1
Bromide SCHEMBL7104246 0.74 BCL2L1 (0.58) TSHRHPGDALDH1A1KDM4ELMNA
SCHEMBL524602 0.74 PNMT (0.63) PNMTHPGDNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250268015-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2025-08-21 US disclosed
EP-4265624-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME Lg Chem, Ltd. (KR) 2023-10-25 EP disclosed
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND LG CHEM, LTD. (KR) 2023-10-05 US disclosed
EP-4194460-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND Lg Chem, Ltd. (KR) 2023-06-14 EP disclosed
CN-115989725-A Compound and organic light emitting device including the same 株式会社LG化学 2023-04-18 CN disclosed
CN-115968592-A Organic light emitting device comprising organic compound 株式会社LG化学 2023-04-14 CN disclosed
CN-115135662-A Iridium complex compound, composition containing iridium complex compound, organic electroluminescent element and method for producing same, organic EL display device, and organic EL lighting device 三菱化学株式会社 2022-09-30 CN disclosed
WO-2022139513-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2022-06-30 WO disclosed
WO-2022139525-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND 주식회사 엘지화학 2022-06-30 WO disclosed
EP-2203055-A1 1-METHYL NICOTINAMIDE AND DERIVATIVES FOR TREATMENT OF GASTRIC INJURY Cortria Corporation (US) 2010-07-07 EP disclosed
US-7304155-B2 Tetrahydrobenzfluorene derivatives N.V. ORGANON (NL) 2007-12-04 US disclosed
US-20050119264-A1 Tetrahydrobenzfluorene derivatives MERCK SHARP & DOHME B.V. (NL) 2005-06-02 US disclosed
US-20050119264-A1 Tetrahydrobenzfluorene derivatives MERCK SHARP & DOHME B.V. (NL) 2005-06-02 US disclosed
EP-1458743-A1 TETRAHYDROBENZFLUORENE DERIVATIVES Akzo Nobel N.V. (NL) 2004-09-22 EP disclosed
WO-2003053994-A1 TETRAHYDROBENZFLUORENE DERIVATIVES AKZO NOBEL N.V. (NL) 2003-07-03 WO disclosed
EP-0832883-B1 Tetrahydrobenzo(a)fluorene compounds and methods of use LILLY CO ELI (US) 2002-04-03 EP disclosed
EP-0832883-B1 Tetrahydrobenzo(a)fluorene compounds and methods of use LILLY CO ELI (US) 2002-04-03 EP disclosed
EP-0832883-A1 Tetrahydrobenzo(a)fluorene compounds and methods of use ELI LILLY AND COMPANY (US) 1998-04-01 EP disclosed
EP-0832883-A1 Tetrahydrobenzo(a)fluorene compounds and methods of use ELI LILLY AND COMPANY (US) 1998-04-01 EP disclosed
EP-0832883-A1 Tetrahydrobenzo(a)fluorene compounds and methods of use ELI LILLY AND COMPANY (US) 1998-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320214-A1 ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC COMPOUND CYP1A1, AOX1, CYP1B1 TSHR 3909/4885PNMT 1201/4885HPGD 2302/4885
US-20050119264-A1 Tetrahydrobenzfluorene derivatives ESR1, ESR2, GPER1 TSHR 129/4885PNMT 2136/4885HPGD 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.