Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817174 | 0.84 | SIGMAR1 (0.42) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 | |
| SCHEMBL2696843 | 0.81 | LMNA (0.42) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 | |
| SCHEMBL2694596 | 0.81 | LMNA (0.42) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 | |
| SCHEMBL2696736 | 0.81 | LMNA (0.42) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 | |
| SCHEMBL339731 | 0.81 | LMNA (0.42) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 | |
| SCHEMBL2694433 | 0.79 | S1PR4 (0.41) | EPHX1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL339773 | 0.79 | SIGMAR1 (0.38) | SIGMAR1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL338887 | 0.79 | SIGMAR1 (0.38) | SIGMAR1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL10781105 | 0.79 | LPAR3 (0.48) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 | |
| SCHEMBL8657353 | 0.79 | LPAR3 (0.48) | SIGMAR1EPHX1S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097752-B2 | Antiprotozoal ring-substituted phospholipids | MAKSCIENTIFIC, LLC (US) | 2012-01-17 | — | — | US | claimed |
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | MAK SCIENTIFIC CORPORATION (US) | 2006-05-18 | — | — | US | claimed |
| US-8097752-B2 | Antiprotozoal ring-substituted phospholipids | MAKSCIENTIFIC, LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | MAK SCIENTIFIC CORPORATION (US) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060105998-A1 | Antiprotozoal ring-substiuted phospholipids | PHOSPHO1, PLTP, PLA2G2C | SIGMAR1 1462/4885EPHX1 184/4885S1PR4 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.