Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052285 | 0.86 | ALDH1A1 (0.46) | KIF11MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL23159756 | 0.81 | ALDH1A1 (0.48) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17174302 | 0.79 | DRD1 (0.39) | MEN1KMT2A | |
| SCHEMBL7887616 | 0.78 | ESR1 (0.52) | KIF11KDM4EALDH1A1TYRNR1I2 | |
| SCHEMBL31376356 | 0.78 | TMEM97 (0.40) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL57369 | 0.78 | MEN1 (0.57) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| Hydroquinone SCHEMBL28076396 | 0.78 | MEN1 (0.57) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL20496423 | 0.78 | NPC1 (0.65) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL29696501 | 0.78 | NPC1 (0.65) | MEN1KMT2ANPC1ALDH1A1LMNA | |
| SCHEMBL17547015 | 0.78 | EGFR (0.44) | MEN1KMT2ANPC1CYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271651-B1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2346887-B1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2013-12-25 | — | — | EP | disclosed |
| US-8546600-B2 | Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite | DOW TECHNOLOGY INVESTMENTS LLC | 2013-10-01 | — | — | US | disclosed |
| EP-2257560-B1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CHEM PLASTIC (US) | 2013-07-17 | — | — | EP | disclosed |
| US-8471066-B2 | Slurry process for phosphoromonochloridite synthesis | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC | 2013-06-25 | — | — | US | disclosed |
| US-8097749-B2 | Isothermal process for phosphoromonochloridite synthesis | Union Carbide Chemical and Plastics Technology Technology | 2012-01-17 | — | — | US | disclosed |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | DOW TECHNOLOGY INVESTMENTS LLC | 2011-08-11 | — | — | US | disclosed |
| US-20110021840-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS | UNION CARBIDE CORPORATION | 2011-01-27 | — | — | US | disclosed |
| EP-2271651-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | Dow Global Technologies Inc. (US) | 2011-01-12 | — | — | EP | disclosed |
| EP-2257560-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | Union Carbide Chemicals & Plastics Technology Llc (Formerly Union Carbide Chemicals & Plastics Technology Corporation) (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009120529-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC (FORMERLY UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION) (US) | 2009-10-01 | — | — | WO | disclosed |
| US-20090247790-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | UNION CARBIDE CORPORATION | 2009-10-01 | — | — | US | disclosed |
| WO-2009120210-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247790-A1 | ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS | PIM3, PLCB3, PLCD1 | KIF11 4163/4885MEN1 1996/4885KMT2A 3341/4885 |
| US-20110196166-A1 | SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE | SOST, PLCB3, PPIP5K2 | KIF11 3145/4885MEN1 1290/4885KMT2A 3288/4885 |
| US-20110021840-A1 | SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYTHESIS | PSPH, SPIN3, SYNGR2 | KIF11 1158/4885MEN1 561/4885KMT2A 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.