Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398387 | 0.82 | PTGS2 (0.53) | PDE4BKMOGAAMAPK1PIN1 | |
| SCHEMBL13425892 | 0.81 | PDE4B (0.44) | PDE4BKMOABCB1ABCG2HPGDS | |
| SCHEMBL3395650 | 0.77 | KMO (0.49) | KMOFYN | |
| SCHEMBL3399530 | 0.74 | PTGS2 (0.49) | PDE4BKDM4EGAA | |
| SCHEMBL16064384 | 0.71 | KMO (0.48) | PDE4BKMOKDM4E | |
| SCHEMBL3400232 | 0.71 | PHGDH (0.43) | F2RL3KDM4EGAA | |
| SCHEMBL3395570 | 0.70 | MAPT (0.47) | F2RL3KDM4CKDM4EGAAMAPK1 | |
| SCHEMBL19436682 | 0.70 | KDM4E (0.60) | KMOKDM4EMAPK1HSD17B10 | |
| SCHEMBL3393979 | 0.70 | PDE4B (0.50) | PDE4B | |
| SCHEMBL25645955 | 0.69 | ESR2 (0.44) | KMOHPGDSF2RL3FYNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |