Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399098 | 0.82 | PDE4B (0.49) | PDE4BKMOPIN1GAAMAPK1 | |
| SCHEMBL13425935 | 0.81 | PTGS2 (0.47) | PTGS2PDE4BKMOPKMMAPT | |
| SCHEMBL8624064 | 0.81 | PTGS2 (0.47) | PTGS2PDE4BKMOMAPTNPC1 | |
| SCHEMBL3395650 | 0.80 | KMO (0.49) | KMOMAPTCNR2MDM2ABL1 | |
| SCHEMBL8311952 | 0.79 | LMNA (0.51) | PTGS2KMOMAPTGAARAB9A | |
| SCHEMBL8311450 | 0.78 | PTGS2 (0.44) | PTGS2PDE4BKMOPIN1MAPT | |
| SCHEMBL3395714 | 0.77 | ENPP3 (0.36) | PDE4BPKMMAPTGAAMAPK1 | |
| SCHEMBL3395627 | 0.77 | ALPL (0.47) | NPC1RAB9A | |
| SCHEMBL3395935 | 0.77 | ENPP3 (0.39) | PTGS2KMOPKMMAPTNPC1 | |
| SCHEMBL3433500 | 0.75 | PDE4B (0.48) | PDE4BNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |