Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426429 | 0.82 | KMO (0.41) | KMOCASP1ABL1MAPTMARS1 | |
| SCHEMBL3398387 | 0.80 | PTGS2 (0.53) | KMOABL1MAPTMDM2CNR2 | |
| SCHEMBL3399098 | 0.77 | PDE4B (0.49) | KMOFYN | |
| SCHEMBL3399530 | 0.75 | PTGS2 (0.49) | MAPTALDH1A1 | |
| SCHEMBL3395627 | 0.74 | ALPL (0.47) | MARS1ENPP3ALPLXIAPALDH1A1 | |
| SCHEMBL3433500 | 0.72 | PDE4B (0.48) | ALPLALDH1A1 | |
| SCHEMBL3434581 | 0.71 | GRM5 (0.44) | MAPTTSHRENPP3ALPLXIAP | |
| SCHEMBL3395935 | 0.71 | ENPP3 (0.39) | KMOMAPTENPP3ALPLXIAP | |
| SCHEMBL3400232 | 0.71 | PHGDH (0.43) | CASP1MAPTRPA1CTSAALDH1A1 | |
| SCHEMBL16064384 | 0.71 | KMO (0.48) | KMOMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |