Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400967 | 0.81 | RAB9A (0.38) | ALDH1A1HPGDADORA2ALMNATSHR | |
| SCHEMBL3406920 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNATSHRKMT2A | |
| SCHEMBL3405612 | 0.77 | L3MBTL1 (0.43) | ALDH1A1HPGDADORA2ALMNATSHR | |
| SCHEMBL1724016 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HPGDLMNATSHRKMT2A | |
| SCHEMBL11278098 | 0.73 | LMNA (0.64) | ALDH1A1LMNAKMT2AHSD17B10MEN1 | |
| SCHEMBL11289442 | 0.73 | MAPT (0.52) | ALDH1A1LMNAKMT2AMAPTGAA | |
| SCHEMBL19981322 | 0.72 | HPGD (0.63) | ALDH1A1HPGDTSHRKMT2AHSD17B10 | |
| SCHEMBL27191747 | 0.72 | MAPT (0.51) | ALDH1A1HPGDLMNATSHRKMT2A | |
| SCHEMBL3399825 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDLMNATSHRKMT2A | |
| SCHEMBL9750566 | 0.71 | CDC7 (0.51) | ALDH1A1HPGDLMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2158199-B1 | PIPERIDINE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-11-17 | — | — | EP | disclosed |