Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401392 | 0.81 | KMT2A (0.44) | KMT2AALDH1A1MEN1HPGDGAA | |
| SCHEMBL3401052 | 0.73 | CYP2C9 (0.65) | KMT2AMEN1SMN1; SMN2NPC1POLB | |
| SCHEMBL10447618 | 0.73 | ALDH1A1 (0.70) | ALDH1A1GAAKDM4ESMN1; SMN2POLB | |
| SCHEMBL3397115 | 0.73 | SMN1; SMN2 (0.56) | KMT2AALDH1A1MEN1HPGDKDM4E | |
| SCHEMBL7879085 | 0.73 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1HPGDGAA | |
| SCHEMBL3400265 | 0.73 | HTR2C (0.46) | KMT2AALDH1A1MEN1HPGDGAA | |
| SCHEMBL3402191 | 0.71 | TP53 (0.45) | KMT2AALDH1A1MEN1HPGDGAA | |
| SCHEMBL18823273 | 0.70 | ALDH1A1 (0.58) | KMT2AALDH1A1MEN1HPGDGAA | |
| SCHEMBL8322979 | 0.70 | DRD2 (0.70) | ALDH1A1HPGDKDM4EL3MBTL1LMNA | |
| SCHEMBL22172135 | 0.69 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247588-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009107850-A2 | FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-09-03 | — | — | WO | disclosed |