Ginkgolide A

Ginkgolide A

SCHEMBL340233

C[C@@H]1C(=O)O[C@H]2C[C@@]34[C@H]5C[C@@H](C(C)(C)C)C36[C@@H](OC(=O)[C@@H]6O)O[C@@]4(C(=O)O5)[C@]21O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GLRA1 P23415 4/20 1.00
GLRA2 P23416 4/20 1.00
KMT2A Q03164 2/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
MEN1 O00255 1/20 1.00
PTAFR P25105 4/20 0.67
CYP2C9 P11712 1/20 0.67
HSD17B10 Q99714 1/20 0.67
GUSB P08236 1/20 0.67
KDM4E B2RXH2 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ginkgolide A SCHEMBL340234 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkgolide A SCHEMBL16452772 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkgolide A SCHEMBL14029426 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkgolide A SCHEMBL29493161 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkgolide A SCHEMBL13808829 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkgolide A SCHEMBL24818724 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkgolide A SCHEMBL13702916 1.00 GLRA1 (1.00) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
Ginkolide B SCHEMBL29384055 0.91 PTAFR (0.83) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
SCHEMBL13702686 0.87 GLRA1 (0.77) GLRA1GLRA2KMT2ASMN1; SMN2MEN1
SCHEMBL13702895 0.87 GLRA1 (0.77) GLRA1GLRA2KMT2ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005544-A Method for preparing VA-ECMO lung injury treatment drug by using ginkgolide A to regulate YARS1 中国人民解放军总医院第八医学中心 2026-05-12 CN claimed
CN-122012537-A Gene GbCYP A6 for promoting synthesis of ginkgolide and application thereof 扬州大学 2026-05-12 CN claimed
US-12622941-B2 Anticoccidial composition comprising ginkgo leaves and use thereof CJ CHEILJEDANG CORPORATION (KR) 2026-05-12 US claimed
US-12611394-B2 Use of ginkgolide a in the treatment of autism CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) 2026-04-28 US claimed
EP-4405047-B1 CANNABINOID FORMULATION FOR ORAL ADMINISTRATION CB21 PHARMA S R O (CZ) 2026-04-01 EP claimed
US-12569483-B2 Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2026-03-10 US claimed
EP-3782619-B1 USE OF GINKGO BILOBA TERPENE LACTONE IN PREPARATION OF DRUGS FOR PREVENTION AND/OR TREATMENT OF TREMORS AND HEALTHCARE PRODUCTS CHENGDU BAIYU PHARMACEUTICAL CO LTD (CN) 2026-02-25 EP claimed
US-12545694-B2 Cannabidiol derivatives, preparation method thereof and use thereof CHENGDU BAIYU PHARMACEUTICAL CO., LTD. (CN) 2026-02-10 US claimed
EP-4630413-A1 FLAVANONE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS Firmenich Incorporated (US) 2025-10-15 EP claimed
US-20250271426-A1 REDUCTION OF BITTER TASTE OF ACTIVE PHARMACEUTICAL INGREDIENTS AND RELATED ASSAYS AND SCREENING METHODS FIRMENICH INCORPORATED (US) 2025-08-28 US claimed
US-5512286-A CONTAINING FLAVONE GLYCOSIDES, GINKGOLIDES AND BILOBALIDES; FREE FROM SERUM-PRECIPITATING AND/OR HAEMAGGLUTINATING COMPONENTS DR. WILLMAR SCHWABE GMBH & CO. (DE) 1996-04-30 US claimed
EP-0431536-B1 A method of preparation of an extract from Gingko biloba leaves. SCHWABE WILLMAR GMBH & CO (DE) 1995-07-19 EP claimed
EP-0477968-B1 Extract from Ginkgo biloba leaves, in particular for intravenous injection or infusion, a method of preparation of the extract and ampoule preparations containing the extract SCHWABE WILLMAR GMBH & CO (DE) 1995-05-03 EP claimed
EP-0436129-B1 Active component concentrates and new active component combinations from Ginkgo biloba leaves, their method of preparation and pharmaceuticals containing the active component concentrates or the active component combinations WALLINGSTOWN COMPANY LIMITED (IE) 1995-04-12 EP claimed
US-5399348-A Extract from Ginkgo biloba leaves, its method of preparation and pharmaceuticals containing the extract DR. WILLMAR SCHWABE GMBH & CO. (DE) 1995-03-21 US claimed
EP-0431535-B1 Extract from Ginkgo biloba leaves, its method of preparation and pharmaceuticals containing the extract SCHWABE WILLMAR GMBH & CO (DE) 1994-03-02 EP claimed
EP-0532512-A4 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS 1993-05-05 EP claimed
EP-0532512-A1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS. ALLERGAN INC (US) 1993-03-24 EP claimed
WO-1991018608-A1 USE OF PLATELET ACTIVATING FACTOR ANTAGONISTS AS ANTI-PRURITIC AGENTS ALLERGAN, INC. (US) 1991-12-12 WO claimed
US-4734280-A PLATELET ACTIVATING FACTOR; ANTISHOCK AGENTS, GINKOLIDES SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1988-03-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545694-B2 Cannabidiol derivatives, preparation method thereof and use thereof CNR1, CNR2, OPRM1 GLRA1 132/4885GLRA2 193/4885KMT2A 2899/4885
US-12569483-B2 Methods for objective assessment of memory, early detection of risk for Alzheimer's disease, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs PSMB3, THRB, GRIN2B GLRA1 545/4885GLRA2 293/4885KMT2A 1593/4885
US-12622941-B2 Anticoccidial composition comprising ginkgo leaves and use thereof ALPI, SI, SLC10A2 GLRA1 1920/4885GLRA2 2261/4885KMT2A 3847/4885
US-12611394-B2 Use of ginkgolide a in the treatment of autism NR2F2, MECP2, NR2C2 GLRA1 631/4885GLRA2 96/4885KMT2A 851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.