Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Phenylmethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.56 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylmethanesulfonic Acid SCHEMBL135008 | 0.97 | CA2 (0.58) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL7208342 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL1565755 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL7098601 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL9812588 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL5858462 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL6959619 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL18419593 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL2057826 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 | |
| Phenylmethanesulfonic Acid SCHEMBL18419589 | 0.95 | CA2 (0.56) | CA2CA1PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943813-B | Preparation method of cannabidiol compound | 上海特化医药科技有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-113087625-B | Method for synthesizing benzyl acetate by utilizing combined catalytic system | 潜江新亿宏有机化工有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-111943813-A | Preparation method of cannabidiol compound | 上海特化医药科技有限公司 | 2020-11-17 | — | — | CN | claimed |
| EP-3337885-B1 | PYRITHIONE PRESERVATIVE SYSTEM IN SOLID RINSE AID PRODUCTS | ECOLAB USA INC (US) | 2020-09-23 | — | — | EP | claimed |
| EP-3039107-B1 | SOLID RINSE AID COMPOSITION AND METHOD OF MAKING SAME | ECOLAB USA INC (US) | 2019-10-23 | — | — | EP | claimed |
| EP-2864461-B1 | SOLID FAST DRAINING/DRYING RINSE AID FOR HIGH TOTAL DISSOLVED SOLID WATER CONDITIONS | ECOLAB USA INC (US) | 2019-05-22 | — | — | EP | claimed |
| EP-2870206-B1 | MARKING REMOVAL AGENT | HÄFFNER GMBH & CO KG (DE) | 2016-05-25 | — | — | EP | claimed |
| EP-2870206-A1 | MARKING REMOVAL AGENT | Häffner GmbH & Co. KG (DE) | 2015-05-13 | — | — | EP | claimed |
| WO-2014006041-A1 | MARKING REMOVAL AGENT | HÄFFNER GMBH & CO. HOLDING KG (DE) | 2014-01-09 | — | — | WO | claimed |
| EP-1709145-B1 | SANITIZING AND CLEANING COMPOSITION AND ITS USE FOR SANITIZING AND/OR CLEANING HARD SURFACES | JOHNSON DIVERSEY INC (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1840197-A1 | Composition for rinsing and drying vehicles | KAO CORPORATION, S.A. (ES) | 2007-10-03 | — | — | EP | claimed |
| EP-1383587-B1 | METHOD FOR REDUCING MALODORS IN HYDROTROPIC COMPOSITIONS | DIAL CORP (US) | 2005-11-09 | — | — | EP | claimed |
| EP-0943644-B1 | Salt stable cationic silicone oil-in-water microemulsion | DOW CORNING (US) | 2004-07-14 | — | — | EP | claimed |
| EP-0602179-B1 | DETERGENT COMPOSITIONS CONTAINING CALCIUM AND POLYHYDROXY FATTY ACID AMIDE | PROCTER & GAMBLE (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0551410-B1 | DETERGENT COMPOSITIONS CONTAINING ANIONIC SURFACTANTS, POLYHYDROXY FATTY ACID AMIDES AND MAGNESIUM | PROCTER & GAMBLE (US) | 1995-09-13 | — | — | EP | claimed |
| US-5162378-A | Cetyl dimethicone copolyol, water, silicone, and alcohol; moisturizer, antiperspirant | REVLON CONSUMER PRODUCTS CORPORATION (US) | 1992-11-10 | — | — | US | claimed |
| EP-0212263-B1 | COMPOSITION FOR THE DEVELOPMENT OF LITHOGRAPHIC PRINTING PLATES | HOECHST CELANESE CORPORATION (US) | 1991-04-17 | — | — | EP | claimed |
| EP-0212263-A2 | Composition for the development of lithographic printing plates | HOECHST CELANESE CORPORATION (US) | 1987-03-04 | — | — | EP | claimed |
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | BEAUTY BIOLABS LLC (US) | 2026-05-19 | — | — | US | disclosed |
| US-4145264-A | AROMATIC O-DICARBOXYLIC ACID NITRILES ELECTROLYZED IN AN ORGANIC LIQUID WITH AN ALKALINE ACTIVATOR | BASF AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | KRT18, HCN4, COL14A1 | CA2 154/4885CA1 455/4885PRSS1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.