SCHEMBL340569

SCHEMBL340569

CCNC(N)C(Cc1ccccc1)[Si](OCC)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.46
SLC6A2 P23975 2/20 0.40
TAAR1 Q96RJ0 2/20 0.40
MAOA P21397 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
CYP2A6 P11509 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
EPHX1 P07099 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339199 0.87 SIGMAR1 (0.47) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL4590848 0.79 CYP2D6 (0.47) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL21060575 0.78 SIGMAR1 (0.42) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL4590844 0.77 ALDH1A1 (0.40) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL2181964 0.76 TAAR1 (0.47) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL339627 0.72 SIGMAR1 (0.42) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL28065353 0.71 SIGMAR1 (0.45) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL22245282 0.69 TAAR1 (0.39) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL1765853 0.69 TRPA1 (0.46) SIGMAR1SLC6A2TAAR1MAOASLC6A4
SCHEMBL1972957 0.68 TAAR1 (0.38) SIGMAR1SLC6A2TAAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070286994-A1 DURABLE ANTIREFLECTIVE FILM 3M INNOVATIVE PROPERTIES COMPANY 2007-12-13 US claimed
US-20150175812-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES CO (US) 2015-06-25 US disclosed
US-20120015002-A1 ANTIMICROBIAL COATINGS 3M INNOVATIVE PROPERTIES COMPANY 2012-01-19 US disclosed
US-20080240479-A1 HYDROPHOBIC AND OLEOPHOBIC COATING AND METHOD FOR PREPARING THE SAME SONIC INNOVATIONS, INC. 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015002-A1 ANTIMICROBIAL COATINGS ARG1, CAPG, CLSPN SIGMAR1 673/4885SLC6A2 3196/4885TAAR1 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.