Cinepazide

Cinepazide

SCHEMBL34092

COc1cc(/C=C/C(=O)N2CCN(CC(=O)N3CCCC3)CC2)cc(OC)c1OC

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.77
KDM4E B2RXH2 6/20 0.77
HPGD P15428 3/20 0.77
KMT2A Q03164 2/20 0.58
TP53 P04637 3/20 0.56
MAPT P10636 2/20 0.56
HSD17B10 Q99714 2/20 0.56
CYP3A4 P08684 2/20 0.56
STAT6 P42226 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CYP2C19 P33261 1/20 0.56
TRPV1 Q8NER1 1/20 0.55
MEN1 O00255 1/20 0.55
ATM Q13315 1/20 0.55
APP P05067 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ACHE P22303 2/20 0.49
BCHE P06276 1/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cinepazide SCHEMBL8839976 1.00 ALDH1A1 (0.77) ALDH1A1KDM4EHPGDKMT2ATP53
Cinepazide SCHEMBL11009911 0.97 KDM4E (0.72) ALDH1A1KDM4EHPGDKMT2ATP53
Cinepazide SCHEMBL27666991 0.96 KDM4E (0.71) ALDH1A1KDM4EHPGDKMT2ATP53
Cinepazide SCHEMBL1062368 0.96 KDM4E (0.71) ALDH1A1KDM4EHPGDKMT2ATP53
SCHEMBL28790703 0.95 ALDH1A1 (0.73) ALDH1A1KDM4EHPGDKMT2ATP53
Fumaric Acid SCHEMBL11710489 0.95 KDM4E (0.69) ALDH1A1KDM4EHPGDKMT2ATP53
SCHEMBL10646641 0.93 KDM4E (0.67) ALDH1A1KDM4EHPGDKMT2ATP53
SCHEMBL10646647 0.93 KDM4E (0.67) ALDH1A1KDM4EHPGDKMT2ATP53
Cinepazic Acid SCHEMBL2734241 0.87 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDKMT2ATP53
Cinepazic Acid SCHEMBL10795476 0.87 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDKMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1093 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118130678-B Liquid chromatography-mass spectrometry detection method for 14 drugs of dizziness, syncope and cerebral apoplexy in blood 中国民用航空局民用航空医学中心 2025-06-10 CN claimed
CN-119950718-A Pharmaceutical composition containing STING agonist and application thereof 杭州星鳌生物科技有限公司 2025-05-09 CN claimed
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-04-24 US claimed
US-20240325362-A1 NOVEL THERAPEUTIC METHOD FOR ENHANCING MITOCHONDRIAL FUNCTION, TREATING MITOCHONDRIAL DISEASES THEREBY, AND COMPOUNDS USED THEREIN STANDIGM INC. (KR) 2024-10-03 US claimed
CN-118130678-A Liquid chromatography-mass spectrometry detection method for 14 drugs of dizziness, syncope and cerebral apoplexy in blood 中国民用航空局民用航空医学中心 2024-06-04 CN claimed
CN-112028856-B Preparation method of cinepazide maleate intermediate 康普药业股份有限公司 2024-03-26 CN claimed
WO-2024051847-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING FACIAL NERVE MICRO-ENTRAPMENT SYNDROME AND USE THEREOF 北京达尔文细胞生物科技有限公司 2024-03-14 WO claimed
WO-2024051845-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING SEQUELAE STAGE FACIAL NERVE PARALYSIS, AND USE THEREOF 北京达尔文细胞生物科技有限公司 2024-03-14 WO claimed
WO-2023183932-A2 MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) NEW YORK UNIVERSITY (US) 2023-09-28 WO claimed
CN-115894507-A Method for synthesizing (+) -canna oensis alkali and application thereof 昆明医科大学 2023-04-04 CN claimed
WO-2002087556-A9 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY ATHEROGENICS INC (US) 2003-03-20 WO claimed
WO-2002087556-A2 PROBUCOL MONOESTERS AND THEIR USE TO INCREASE PLASMA HDL CHOLESTEROL LEVELS AND IMPROVE HDL FUNCTIONALITY ATHEROGENICS, INC. (US) 2002-11-07 WO claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-5830497-A Medicated plaster containing basic physiologically active agents and/or salts thereof NITTO DENKO CORPORATION (JP) 1998-11-03 US claimed
EP-0580860-B1 METHOD OF MANUFACTURING SOLID DISPERSION NIPPON SHINYAKU CO LTD (JP) 1997-10-22 EP claimed
EP-0387751-B1 Medicated plasters NITTO DENKO CORP (JP) 1994-06-08 EP claimed
WO-1993008801-A1 PREVENTION OF DRUG-INDUCED AGRANULOCYTOSIS WITH FREE RADICAL SCAVENGERS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-05-13 WO claimed
EP-0387751-A2 Medicated plasters NITTO DENKO CORPORATION (JP) 1990-09-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129016-A1 PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF RCC2, PPOX, FTO ALDH1A1 2660/4885KDM4E 290/4885HPGD 1203/4885
US-20240325362-A1 NOVEL THERAPEUTIC METHOD FOR ENHANCING MITOCHONDRIAL FUNCTION, TREATING MITOCHONDRIAL DISEASES THEREBY, AND COMPOUNDS USED THEREIN MCU, NLN, FH ALDH1A1 3088/4885KDM4E 1832/4885HPGD 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.