Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 9/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 9/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1657696 | 0.81 | LTB4R (0.41) | LTB4RLTB4R2L3MBTL1TSHRRAB9A | |
| SCHEMBL29894648 | 0.67 | RAB9A (0.55) | L3MBTL1TSHRRAB9AALDH1A1HTT | |
| SCHEMBL15650312 | 0.67 | ALDH1A1 (0.70) | LTB4RLTB4R2RAB9AALDH1A1HTT | |
| SCHEMBL3412933 | 0.66 | NAAA (0.38) | HTTCNR2CNR1 | |
| SCHEMBL6973527 | 0.64 | LTB4R (0.46) | LTB4RLTB4R2RAB9AALDH1A1HTT | |
| SCHEMBL6974366 | 0.64 | LTB4R (0.45) | LTB4RLTB4R2RAB9AALDH1A1HTT | |
| SCHEMBL296937 | 0.64 | ALDH1A1 (0.64) | RAB9AALDH1A1HTTCNR2 | |
| SCHEMBL1788036 | 0.63 | MEN1 (0.43) | TSHRRAB9AALDH1A1HTTNPC1 | |
| SCHEMBL18773733 | 0.63 | AOC3 (0.56) | L3MBTL1TSHRRAB9AALDH1A1HTT | |
| SCHEMBL12809403 | 0.63 | RAB9A (0.50) | L3MBTL1TSHRRAB9AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-A2 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | Edison Pharmaceuticals, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111576-A2 | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |