Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2068526 | 0.93 | LMNA (0.82) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL11785265 | 0.89 | LMNA (0.77) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL21836007 | 0.85 | LMNA (0.66) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL4623054 | 0.84 | ALDH1A1 (0.75) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL522424 | 0.82 | LMNA (0.72) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL27995939 | 0.81 | KEAP1 (0.72) | LMNAALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL9156459 | 0.81 | GAA (0.71) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL4376657 | 0.81 | LMNA (0.70) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL398000 | 0.81 | LMNA (0.70) | LMNACYP2C9CYP2C19USP2ALDH1A1 | |
| SCHEMBL2068110 | 0.81 | LMNA (0.70) | LMNACYP2C9CYP2C19USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160304-A1 | AROMATIC SULFONE COMPOUND AS ALDOSTERONE RECEPTOR MODULATOR | NR3C2, AGTR1, AGTR2 | LMNA 4244/4885CYP2C9 201/4885CYP2C19 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.