Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 20-Hydroxyecdysone SCHEMBL20033388 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL8861142 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL8193574 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL8193572 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL17580332 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL22087 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL990951 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL8861138 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL6243068 | 0.93 | MEN1 (0.71) | MEN1KMT2A | |
| 20-Hydroxyecdysone SCHEMBL13576228 | 0.93 | MEN1 (0.71) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243263-B2 | Steroidal ligands and their use in gene switch modulation | INTREXON CORPORATION (US) | 2016-01-26 | — | — | US | claimed |
| US-20140057349-A1 | Steroidal Ligands and Their Use in Gene Switch Modulation | INTREXON CORPORATION (US) | 2014-02-27 | — | — | US | claimed |
| EP-2265116-A2 | STEROIDAL LIGANDS AND THEIR USE IN GENE SWITCH MODULATION | Intrexon Corporation (US) | 2010-12-29 | — | — | EP | claimed |
| US-20090298175-A1 | Steroidal Ligands and Their Use in Gene Switch Modulation | INTREXON CORPORATION | 2009-12-03 | — | — | US | claimed |
| WO-2009114201-A2 | STEROIDAL LIGANDS AND THEIR USE IN GENE SWITCH MODULATION | INTREXON CORPORATION (US) | 2009-09-17 | — | — | WO | claimed |
| US-20070292967-A1 | Assay for Ligands of the Ecdysone Receptor | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) | 2007-12-20 | — | — | US | claimed |
| EP-1720894-A1 | ASSAY FOR LIGANDS OF THE ECDYSONE RECEPTOR | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2006-11-15 | — | — | EP | claimed |
| WO-2005054271-A1 | ASSAY FOR LIGANDS OF THE ECDYSONE RECEPTOR | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2005-06-16 | — | — | WO | claimed |
| US-20180348231-A1 | LIGAND INDUCIBLE POLYPEPTIDE COUPLER SYSTEM | INTREXON CORPORATION (US) | 2018-12-06 | — | — | US | disclosed |
| EP-3278110-A1 | LIGAND INDUCIBLE POLYPEPTIDE COUPLER SYSTEM | Intrexon Corporation (US) | 2018-02-07 | — | — | EP | disclosed |
| US-20170275600-A1 | MODIFIED FORMS OF PSEUDOMONAS EXOTOXIN A | INTREXON CORPORATION (US) | 2017-09-28 | — | — | US | disclosed |
| US-9677055-B2 | Modified forms of Pseudomonas exotoxin A | INTERXON CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-20170037386-A1 | MODIFIED FORMS OF PSEUDOMONAS EXOTOXIN A | INTREXON CORPORATION (US) | 2017-02-09 | — | — | US | disclosed |
| WO-2016160791-A1 | LIGAND INDUCIBLE POLYPEPTIDE COUPLER SYSTEM | INTREXON CORPORATION (US) | 2016-10-06 | — | — | WO | disclosed |
| EP-2265116-A2 | STEROIDAL LIGANDS AND THEIR USE IN GENE SWITCH MODULATION | Intrexon Corporation (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20090298175-A1 | Steroidal Ligands and Their Use in Gene Switch Modulation | INTREXON CORPORATION | 2009-12-03 | — | — | US | disclosed |
| WO-2009114201-A2 | STEROIDAL LIGANDS AND THEIR USE IN GENE SWITCH MODULATION | INTREXON CORPORATION (US) | 2009-09-17 | — | — | WO | disclosed |
| US-20070292967-A1 | Assay for Ligands of the Ecdysone Receptor | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) | 2007-12-20 | — | — | US | disclosed |
| EP-1720894-A1 | ASSAY FOR LIGANDS OF THE ECDYSONE RECEPTOR | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005054271-A1 | ASSAY FOR LIGANDS OF THE ECDYSONE RECEPTOR | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275600-A1 | MODIFIED FORMS OF PSEUDOMONAS EXOTOXIN A | CD4, CD47, CD14 | MEN1 3041/4885KMT2A 2781/4885 |
| US-20070292967-A1 | Assay for Ligands of the Ecdysone Receptor | OR51E2, FSHR, ESRRB | MEN1 3825/4885KMT2A 4195/4885 |
| US-20180348231-A1 | LIGAND INDUCIBLE POLYPEPTIDE COUPLER SYSTEM | MST1R, GRPR, GHITM | MEN1 2513/4885KMT2A 4636/4885 |
| US-20090298175-A1 | Steroidal Ligands and Their Use in Gene Switch Modulation | ESRRB, NR3C1, ESRRA | MEN1 4342/4885KMT2A 2717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.