Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381321 | 0.81 | GAA (0.51) | ALDH1A1HTTKMT2AMEN1LMNA | |
| SCHEMBL7379862 | 0.81 | GAA (0.51) | ALDH1A1HTTKMT2AMEN1LMNA | |
| SCHEMBL7384133 | 0.81 | GAA (0.51) | ALDH1A1HTTKMT2AMEN1LMNA | |
| SCHEMBL15782481 | 0.81 | MGLL (0.48) | ALDH1A1HSP90AA1NPSR1TDP1HPGD | |
| SCHEMBL18639174 | 0.81 | MGLL (0.44) | ALDH1A1HSP90AA1NPSR1TDP1HPGD | |
| SCHEMBL8372896 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HSP90AA1NPSR1TDP1HPGD | |
| SCHEMBL2348816 | 0.78 | MGLL (0.53) | ALDH1A1HSP90AA1NPSR1TDP1HPGD | |
| SCHEMBL3414901 | 0.77 | MGLL (0.54) | ALDH1A1HSP90AA1NPSR1TDP1HPGD | |
| SCHEMBL19309442 | 0.76 | MGLL (0.46) | ALDH1A1HSP90AA1NPSR1TDP1HPGD | |
| SCHEMBL11030830 | 0.73 | HPGD (0.50) | ALDH1A1HSP90AA1NPSR1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712423-B2 | Methods and compositions for modifying mucous membranes | ABBOTT NICHOLAS L (US) | 2023-08-01 | — | — | US | disclosed |
| EP-2443144-A1 | SAP VARIANTS AND THEIR USE | Promedior, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010148234-A1 | SAP VARIANTS AND THEIR USE | PROMEDIOR, INC. (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20080305038-A1 | Transport of Nano-and Macromolecular Structures Into Cytoplasm and Nucleus of Cells | LUDWIG-MAXIMILIANS-UNIVERSITÄT (DE) | 2008-12-11 | — | — | US | disclosed |
| WO-1999059643-A2 | LIPOSOMAL DELIVERY COMPLEX | SDG, INC. (US) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080305038-A1 | Transport of Nano-and Macromolecular Structures Into Cytoplasm and Nucleus of Cells | NFATC1, KPNA4, KPNA1 | ALDH1A1 4161/4885HSP90AA1 2014/4885NPSR1 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.