Phosphoric Acid

Phosphoric Acid

SCHEMBL3417079

CC1(C)C2=C(Cl)C(=O)C(Cl)=CC2=Nc2ccc(O)cc21.O=P(O)(O)O

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10293371 0.85 OPRM1 (0.32)
SCHEMBL31119923 0.83
SCHEMBL1825576 0.81 CASP3 (0.35)
SCHEMBL20777534 0.78 GLA (0.33)
SCHEMBL6933106 0.68
SCHEMBL562630 0.68 ALDH1A1 (0.33)
SCHEMBL14077242 0.67 ALDH1A1 (0.30)
SCHEMBL661200 0.64 MEN1 (0.39)
SCHEMBL31142510 0.64 MEN1 (0.39)
SCHEMBL13996842 0.58 ESR2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
WO-2010028349-A2 FLUOROCHROMES FOR ORGANELLE TRACING AND MULTI-COLOR IMAGING ENZO LIFE SCIENCES, INC. (US) 2010-03-11 WO disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 US disclosed
US-20090170144-A1 DETERMINATION OF VIABLE MICROORGANISMS USING COATED PARAMAGNETIC BEADS UNIVERSITY OF CINCINNATI 2009-07-02 US disclosed
US-20050079484-A1 Method of detecting biological materials in liquid CINCINNATI, UNIVERSITY OF 2005-04-14 US disclosed