Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178329 | 0.80 | CYP1A2 (0.45) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL841631 | 0.80 | P2RX3 (0.42) | HASPINPLAUALDH1A1 | |
| SCHEMBL30399803 | 0.80 | PLAU (0.40) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL11084669 | 0.80 | PIK3CA (0.39) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL3192300 | 0.80 | PLAU (0.40) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL2724076 | 0.78 | GAA (0.39) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL29560817 | 0.78 | DCK (0.39) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL10998174 | 0.78 | FTO (0.39) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL22833803 | 0.78 | HASPIN (0.37) | HASPINCYP1A2PIK3CAFTOALKBH5 | |
| SCHEMBL30067848 | 0.78 | HASPIN (0.37) | HASPINCYP1A2PIK3CAFTOALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452355-B | Self-repairing rat-proof and termite-proof polyurethane, preparation method and application | 安徽建筑大学 | 2021-07-16 | — | — | CN | claimed |
| EP-3362100-B1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2022-06-22 | — | — | EP | disclosed |
| CN-110452355-B | Self-repairing rat-proof and termite-proof polyurethane, preparation method and application | 安徽建筑大学 | 2021-07-16 | — | — | CN | disclosed |
| US-10729738-B2 | Hindered disulfide drug conjugates | GENENTECH, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2017-04-27 | — | — | US | disclosed |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2017-04-27 | — | — | US | disclosed |
| WO-2017064675-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| US-8252791-B2 | Purine compounds as cannabinoid receptor blockers | JENRIN DISCOVERY, INC. (US) | 2012-08-28 | — | — | US | disclosed |
| US-20100041650-A1 | PURINE COMPOUNDS AS CANNABINOID RECEPTOR BLOCKERS | JENRIN DISCOVERY (US) | 2010-02-18 | — | — | US | disclosed |
| WO-2010019762-A1 | PURINE COMPOUNDS AS CANNABINOID RECEPTOR BLOCKERS | JENRIN DISCOVERY (US) | 2010-02-18 | — | — | WO | disclosed |
| WO-2008071962-A1 | PTERIDINES AND PYRIMIDINOPYRIDINES AS ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2008-06-19 | — | — | WO | disclosed |
| EP-0184738-A2 | Imidazole derivatives, medicaments containing these compounds, and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041650-A1 | PURINE COMPOUNDS AS CANNABINOID RECEPTOR BLOCKERS | CNR1, CNR2, P2RY1 | HASPIN 2023/4885CYP1A2 600/4885PIK3CA 973/4885 |
| US-10729738-B2 | Hindered disulfide drug conjugates | STS, TST, SCLY | HASPIN 1345/4885CYP1A2 320/4885PIK3CA 4317/4885 |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | STS, TST, SCLY | HASPIN 1345/4885CYP1A2 320/4885PIK3CA 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.