Sugi Predict

Sugi Predict / Compounds / SCHEMBL841631

SCHEMBL841631

SCHEMBL841631

COc1ncc(OC)c(N)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ P2RX3 P56373 12/20 0.42
▸ P2RX2 Q9UBL9 12/20 0.42
▸ TLR8 Q9NR97 1/20 0.40
▸ HASPIN Q8TF76 1/20 0.38
▸ PLAU P00749 2/20 0.38
▸ TUBB4A P04350 1/20 0.38
▸ TUBB P07437 1/20 0.38
▸ TUBA3C P0DPH7 1/20 0.38
▸ TUBA1B P68363 1/20 0.38
▸ TUBA4A P68366 1/20 0.38
▸ TUBB4B P68371 1/20 0.38
▸ TUBB3 Q13509 1/20 0.38
▸ TUBB2A Q13885 1/20 0.38
▸ TUBB8 Q3ZCM7 1/20 0.38
▸ TUBA3E Q6PEY2 1/20 0.38
▸ TUBA1A Q71U36 1/20 0.38
▸ TUBA1C Q9BQE3 1/20 0.38
▸ TUBB6 Q9BUF5 1/20 0.38
▸ TUBB2B Q9BVA1 1/20 0.38
▸ TUBB1 Q9H4B7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3417149 0.80 P2RX3 (0.60) P2RX3P2RX2ALDH1A1
SCHEMBL3417147 0.80 HASPIN (0.39) HASPINPLAUALDH1A1
SCHEMBL30068211 0.78 P2RX3 (0.54) P2RX3P2RX2TLR8
SCHEMBL5957155 0.78 P2RX3 (0.54) P2RX3P2RX2TLR8
SCHEMBL11084669 0.78 PIK3CA (0.39) HASPINPLAU
SCHEMBL2724076 0.77 GAA (0.39) P2RX3P2RX2HASPINPLAU
SCHEMBL29560817 0.77 DCK (0.39) P2RX3P2RX2HASPINPLAU
SCHEMBL30151419 0.77 KDM4E (0.52) P2RX3P2RX2TLR8ALDH1A1
SCHEMBL13530552 0.77 DCK (0.39) P2RX3P2RX2HASPINPLAU
SCHEMBL30067848 0.77 HASPIN (0.37) P2RX3P2RX2HASPINPLAUALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651261-B Method for synthesizing 4-amino-2, 5-dimethoxypyrimidine by one-pot method 江苏快达农化股份有限公司 2022-05-20 — — CN claimed
CN-106243045-A A kind of preparation method of 2,5 dimethoxy 4 aminopyrimidines 常州大学 2016-12-21 — — CN claimed
CN-110959138-B Resist material DIC株式会社 2023-06-30 — — CN disclosed
US-11487204-B2 Resist material DIC CORPORATION (JP) 2022-11-01 — — US disclosed
CN-109651261-B Method for synthesizing 4-amino-2, 5-dimethoxypyrimidine by one-pot method 江苏快达农化股份有限公司 2022-05-20 — — CN disclosed
CN-109651261-B Method for synthesizing 4-amino-2, 5-dimethoxypyrimidine by one-pot method 江苏快达农化股份有限公司 2022-05-20 — — CN disclosed
CN-109651261-B Method for synthesizing 4-amino-2, 5-dimethoxypyrimidine by one-pot method 江苏快达农化股份有限公司 2022-05-20 — — CN disclosed
CN-108368214-B Novolac resin and resist film DIC株式会社 2021-03-23 — — CN disclosed
CN-108368213-B Novolac resin and resist film DIC株式会社 2020-12-18 — — CN disclosed
CN-107003612-B Photosensitive composition for forming resist underlayer film, and resist underlayer film DIC株式会社 2020-11-06 — — CN disclosed
US-20200166838-A1 RESIST MATERIAL DIC CORPORATION (JP) 2020-05-28 — — US disclosed
EP-1375540-A1 ETHYLENIC FLUOROMONOMER CONTAINING HYDROXYL OR FLUOROALKYLCARBONYL GROUP AND FLUOROPOLYMER OBTAINED BY POLYMERIZING THE SAME Daikin Industries, Ltd. (JP) 2004-01-02 — — EP disclosed
US-20040002575-A1 Fluorine-containing ethylenic monomer having hydroxyl group or fluoroalkyl carbonyl group and fluorine-containing polymer prepared by polymerization of same DAIKIN INDUSTRIES, LTD. 2004-01-01 — — US disclosed
US-6620932-B2 2-alkoxy group may be introduced into the appropriate pyrimidine derivatives at the start of the reaction DEGUSSA AG (DE) 2003-09-16 — — US disclosed
US-20030152864-A1 Novel fluorine-containing polymer having acid-reactive group and chemically amplifying type photoresist composition prepared from same DAIKIN INDUSTRIES, LTD. 2003-08-14 — — US disclosed
US-20030022908-A1 2-alkoxy-5-methoxypyrimidines or their tautomeric forms and methods for producing the same DEGUSSA AG (DE) 2003-01-30 — — US disclosed
EP-1275666-A1 NOVEL FLUOROPOLYMER HAVING ACID-REACTIVE GROUP AND CHEMICAL AMPLIFICATION TYPE PHOTORESIST COMPOSITION CONTAINING THE SAME Daikin Industries, Ltd. (JP) 2003-01-15 — — EP disclosed
EP-1274690-A1 2-ALKOXY-5-METHOXYPYRIMIDINES OR THEIR TAUTOMERIC FORMS AND METHODS FOR PRODUCING THE SAME Degussa AG (DE) 2003-01-15 — — EP disclosed
WO-2001081320-A1 2-ALKOXY-5-METHOXYPYRIMIDINES OR THEIR TAUTOMERIC FORMS AND METHODS FOR PRODUCING THE SAME DEGUSSA AG (DE) 2001-11-01 — — WO disclosed
US-6090518-A HAVING HIGH RESOLUTION, WHICH IS USEFUL FOR A HALFMICRONLITHOGRAPHY EMPLOYING A RADIATION MITSUBISHI CHEMICAL CORPORATION (JP) 2000-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11487204-B2 Resist material FLNA, AFF1, RXRA P2RX3 1319/4885P2RX2 1396/4885TLR8 2111/4885
US-20030022908-A1 2-alkoxy-5-methoxypyrimidines or their tautomeric forms and methods for producing the same DPYD, TYMP, UMPS P2RX3 2345/4885P2RX2 1440/4885TLR8 3756/4885
US-20200166838-A1 RESIST MATERIAL FLNA, AFF1, RXRA P2RX3 1319/4885P2RX2 1396/4885TLR8 2111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.