Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381954 | 0.87 | FLT3 (0.48) | HRH4AHRNCEH1 | |
| SCHEMBL28690110 | 0.85 | HRH4 (0.42) | HRH4AHRNCEH1 | |
| SCHEMBL3411403 | 0.80 | DAO (0.50) | KDM4EMAPT | |
| SCHEMBL3418189 | 0.80 | ALOX15 (0.52) | HRH4KDM4E | |
| SCHEMBL3414920 | 0.80 | DAO (0.50) | AHRKDM4E | |
| SCHEMBL3420585 | 0.78 | FLT3 (0.54) | HRH4KDM4EMAPTL3MBTL1 | |
| SCHEMBL1833251 | 0.77 | KDM4E (0.55) | KDM4EMAPTL3MBTL1 | |
| SCHEMBL30920180 | 0.74 | KDM4E (0.59) | HRH4KDM4EMAPT | |
| SCHEMBL1647680 | 0.74 | KDM4E (0.59) | HRH4KDM4EMAPT | |
| SCHEMBL112135 | 0.74 | GPR35 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149554-A1 | Indolyamides as modulators for an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-02-03 | — | — | EP | disclosed |