SCHEMBL3418379

SCHEMBL3418379

Cc1cc(C(C)(C)c2ccc(OC#N)c(C)c2)ccc1OC#N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.44
KDM4E B2RXH2 4/20 0.37
VDR P11473 4/20 0.34
ESR2 Q92731 2/20 0.33
RECQL P46063 1/20 0.32
HSD17B10 Q99714 2/20 0.32
CASP1 P29466 1/20 0.32
KLF10 Q13118 1/20 0.32
MRGPRX4 Q96LA9 2/20 0.32
AR P10275 3/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR6 P50406 1/20 0.31
ESRRG P62508 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CYP19A1 P11511 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30003058 1.00 ESR1 (0.44) ESR1KDM4EVDRESR2RECQL
SCHEMBL29664065 1.00 ESR1 (0.44) ESR1KDM4EVDRESR2RECQL
SCHEMBL3416065 0.81 ESR1 (0.33) ESR1ESR2HSD17B10CASP1KLF10
SCHEMBL8961762 0.81 ESR1 (0.33) ESR1ESR2HSD17B10CASP1KLF10
SCHEMBL29664139 0.79 RORC (0.39) ESR1ESR2ARL3MBTL1
SCHEMBL3421381 0.79 RORC (0.39) ESR1ESR2ARL3MBTL1
SCHEMBL8985167 0.78 GAA (0.44) HSD17B10ARCYP3A4HPGDTSHR
SCHEMBL29489134 0.78 GAA (0.44) HSD17B10ARCYP3A4HPGDTSHR
SCHEMBL11033634 0.78 ALDH1A1 (0.38) KDM4EMRGPRX4ARCYP3A4HPGD
SCHEMBL8961984 0.76 PTGDR2 (0.40) ESR1KDM4EESR2ARCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438146-B1 CYANIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING SAME, RESIN COMPOSITION, CURED ARTICLE, PREPREG, SEALING MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, ADHESIVE AGENT, METAL FOIL-CLAD LAMINATE PLATE, RESIN SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL CO (JP) 2026-04-08 EP disclosed
US-12534617-B2 Resin composition, cured product, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-01-27 US disclosed
US-12486371-B2 Thermally curable resin composition, cured object, resin sheet, prepreg, metal-clad laminate, multilayered printed wiring board, sealing material, fiber-reinforced composite material, adhesive, and semiconductor device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-12-02 US disclosed
EP-3805293-B1 RESIN COMPOSITION, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL CO (JP) 2025-09-17 EP disclosed
EP-4610285-A1 RESIN COMPOSITION, CURED PRODUCT, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-03 EP disclosed
EP-4610287-A1 RESIN COMPOSITION, CURED PRODUCT, PREPREG, METAL FOIL-CLAD LAMINATE, RESIN COMPOSITE SHEET, AND PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-09-03 EP disclosed
US-12312323-B2 Compound, method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-05-27 US disclosed
US-20250109222-A1 CYCLIC ORGANOSILOXANE CONTAINING IMIDE BOND AND POLYMERIZABLE UNSATURATED BOND, AND CURABLE RESIN COMPOSITION COMPRISING SAID CYCLIC ORGANOSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-03 US disclosed
WO-2024213237-A1 CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-10-17 WO disclosed
EP-4438655-A1 CYCLIC ORGANOSILOXANE CONTAINING IMIDE BOND AND POLYMERIZABLE UNSATURATED BOND, AND CURABLE RESIN COMPOSITION COMPRISING SAID CYCLIC ORGANOSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-10-02 EP disclosed
US-20090170983-A1 Cyanato Group-Containing Cyclic Phosphazene Compound and Method for Producing The Same FUSHIMI PHARMACEUTICAL CO., LTD. (JP) 2009-07-02 US disclosed
US-7115681-B2 polyimide resin and a thermosetting resin; can be bonded and cured at a comparatively low temperature, is soluble in a solvent and has excellent heat resistance and adhesion KANEKA CORPORATION (JP) 2006-10-03 US disclosed
US-20060115670-A1 Thermoplastic polyimide resin film, multilayer body and method for manufacturing printed wiring board composed of same KANEKA CORPORATION (JP) 2006-06-01 US disclosed
US-20040176526-A1 Resin composition KANEKA CORPORAITON (JP) 2004-09-09 US disclosed
US-6225492-B1 CONTACTING CYANATE CRUDE PRODUCT SOLUTION COMPRISING CYANATE, UNSUBSTITUTED PHENOL AND NON-ALCOHOLIC SOLVENT WITH POOR SOLVENT CONTAINING ALCOHOL AND WATER TO CRYSTALLIZE OR PRECIPITATE SAID CYANATE SUMITOMO CHEMICAL CO., LTD. (JP) 2001-05-01 US disclosed
EP-0739879-B1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL CO (JP) 1999-12-22 EP disclosed
EP-0739879-A1 Halogen-containing cyanate ester, process for producing the same and thermosetting resin composition containing the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-30 EP disclosed
US-5550282-A CURABLE COMPOSITION COMPRISING PARTIALLY TRIMERIZED PREPOLYMER OF AROMATIC DICYANATE ESTER KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-08-27 US disclosed
US-5488144-A Bifunctional aromatic cyanates, prepolymers and electrical laminates made therefrom KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-01-30 US disclosed
EP-0548970-A2 Prepolymers from bifunctional aromatic cyanates and electrical laminates made therefrom KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170983-A1 Cyanato Group-Containing Cyclic Phosphazene Compound and Method for Producing The Same CENPE, CPNE4, MCM3 ESR1 3389/4885KDM4E 38/4885VDR 4850/4885
US-20250109222-A1 CYCLIC ORGANOSILOXANE CONTAINING IMIDE BOND AND POLYMERIZABLE UNSATURATED BOND, AND CURABLE RESIN COMPOSITION COMPRISING SAID CYCLIC ORGANOSILOXANE ZYX, MUS81, H1-0 ESR1 1058/4885KDM4E 1959/4885VDR 657/4885
US-12534617-B2 Resin composition, cured product, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board CHRM1, MRPL37, MRPL38 ESR1 346/4885KDM4E 967/4885VDR 2665/4885
US-12312323-B2 Compound, method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device ASH2L, RER1, SEM1 ESR1 764/4885KDM4E 1940/4885VDR 4305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.