SCHEMBL342249

SCHEMBL342249

O=C(O)CN(CC(=O)O)c1ccc(Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 2/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MIF P14174 1/20 0.44
TSHR P16473 2/20 0.43
POLB P06746 2/20 0.42
CNR2 P34972 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
GABBR2 O75899 3/20 0.39
GABBR1 Q9UBS5 3/20 0.39
LMNA P02545 2/20 0.39
CYP2C9 P11712 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038936 0.89 TDP1 (0.44) ALDH1A1ALOX15MAPTSMN1; SMN2NPC1
SCHEMBL1633085 0.88 CNR2 (0.51) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL13603843 0.86 ALDH1A1 (0.42) ALDH1A1ALOX15MAPTSMN1; SMN2NPC1
SCHEMBL3349327 0.85 CNR2 (0.43) ALDH1A1ALOX15MAPTSMN1; SMN2NPC1
SCHEMBL3347146 0.82 CNR2 (0.47) ALDH1A1MAPTSMN1; SMN2POLBCNR2
SCHEMBL13603931 0.81 NPC1 (0.45) ALDH1A1ALOX15MAPTSMN1; SMN2NPC1
SCHEMBL6934556 0.81 TDP1 (0.37) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL13645018 0.80 CA2 (0.46) ALDH1A1MAPTPOLBLMNACYP3A4
SCHEMBL202173 0.79 TDP1 (0.50) ALDH1A1SMN1; SMN2NPC1RAB9ATSHR
SCHEMBL8541381 0.79 ALDH1A1 (0.45) ALDH1A1ALOX15MAPTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US claimed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US claimed
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-2471655-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2016-08-17 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-1431032-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2015-12-09 EP disclosed
CN-102529310-B Original edition of lithographic printing plate and lithographic process FUJI FILM CORP. (JP) 2015-09-16 CN disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8435720-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2013-05-07 US disclosed
CN-102653158-A Lithographic printing plate precursor and plate making method thereof FUJIFILM CORP 2012-09-05 CN disclosed
WO-2000048836-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2000-08-24 WO disclosed
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US disclosed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US disclosed
US-5888700-A NONFOGGING, SHELF LIFE KODAK POLYCHROME GRPAHICS, LLC (US) 1999-03-30 US disclosed
US-5821030-A DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER KODAK POLYCHROME GRAPHICS (US) 1998-10-13 US disclosed
US-5776655-A CONTAINING PHOTOPOLYMER EASTMAN KODAK COMPANY (US) 1998-07-07 US disclosed
EP-0795790-A2 Peel-developable lithographic printing plate EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed
US-5629354-A Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0730201-A1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates EASTMAN KODAK COMPANY (US) 1996-09-04 EP disclosed